Exploration
Accueil
Racine
Exploration
Accueil
Racine

Serveur d'exploration sur les relations entre la France et l'Australie

Attention, ce site est en cours de développement !
Attention, site généré par des moyens informatiques à partir de corpus bruts.
Les informations ne sont donc pas validées.

Age- and Sex-Specific Causal Effects of Adiposity on Cardiovascular Risk Factors

Identifieur interne : 003202 ( Main/Exploration ); précédent : 003201; suivant : 003203

Age- and Sex-Specific Causal Effects of Adiposity on Cardiovascular Risk Factors

Auteurs : Tove Fall [Suède] ; Sara H Gg [Suède] ; Alexander Ploner [Suède] ; Reedik M Gi [Estonie] ; Krista Fischer [Estonie] ; Harmen H. M. Draisma [Pays-Bas] ; Antti-Pekka Sarin [Finlande] ; Beben Benyamin [Australie] ; Claes Ladenvall [Suède] ; Mikael Kerlund [Suède] ; Mart Kals [Estonie] ; T Nu Esko [Estonie, États-Unis] ; Christopher P. Nelson [Royaume-Uni] ; Marika Kaakinen [Finlande] ; Ville Huikari [Finlande] ; Massimo Mangino [Royaume-Uni] ; Aline Meirhaeghe [France] ; Kati Kristiansson [Finlande] ; Marja-Liisa Nuotio [Finlande] ; Michael Kobl [Allemagne] ; Harald Grallert [Allemagne] ; Abbas Dehghan [Pays-Bas] ; Maris Kuningas [Pays-Bas] ; Paul S. De Vries [Pays-Bas] ; Renée F. A. G. De Bruijn [Pays-Bas] ; Sara M. Willems [Pays-Bas] ; Kauko Heikkil [Finlande] ; Karri Silventoinen [Finlande] ; Kirsi H. Pietil Inen [Finlande] ; Vanessa Legry [France] ; Vilmantas Giedraitis [Suède] ; Louisa Goumidi [France] ; Ann-Christine Syv Nen [Suède] ; Konstantin Strauch [Allemagne] ; Wolfgang Koenig [Allemagne] ; Peter Lichtner [Allemagne] ; Christian Herder [Allemagne] ; Aarno Palotie [Finlande, États-Unis] ; Cristina Menni [Royaume-Uni] ; André G. Uitterlinden [Pays-Bas] ; Kari Kuulasmaa [Finlande] ; Aki S. Havulinna [Finlande] ; Luis A. Moreno [Espagne] ; Marcela Gonzalez-Gross [Espagne] ; Alun Evans [Royaume-Uni] ; David-Alexandre Tregouet [France] ; John W. G. Yarnell [Royaume-Uni] ; Jarmo Virtamo [Finlande] ; Jean Ferrières [France] ; Giovanni Veronesi [Italie] ; Markus Perola [Finlande] ; Dominique Arveiler [France] ; Paolo Brambilla [Italie] ; Lars Lind [Suède] ; Jaakko Kaprio [Finlande] ; Albert Hofman [Pays-Bas] ; Bruno H. Stricker [Pays-Bas] ; Cornelia M. Van Duijn [Pays-Bas] ; M. Arfan Ikram [Pays-Bas] ; Oscar H. Franco [Pays-Bas] ; Dominique Cottel [France] ; Jean Dallongeville [France] ; Alistair S. Hall [Royaume-Uni] ; Antti Jula [Finlande] ; Martin D. Tobin [Royaume-Uni] ; Brenda W. Penninx [Pays-Bas] ; Annette Peters [Allemagne] ; Christian Gieger [Allemagne] ; Nilesh J. Samani [Royaume-Uni] ; Grant W. Montgomery [Australie] ; John B. Whitfield [Australie] ; Nicholas G. Martin [Australie] ; Leif Groop [Finlande, Suède] ; Tim D. Spector [Royaume-Uni] ; Patrik K. Magnusson [Suède] ; Philippe Amouyel [France] ; Dorret I. Boomsma [Pays-Bas] ; Peter M. Nilsson [Suède] ; Marjo-Riitta J Rvelin [Finlande, Royaume-Uni] ; Valeriya Lyssenko [Suède, Danemark] ; Andres Metspalu [Estonie] ; David P. Strachan [Royaume-Uni] ; Veikko Salomaa [Finlande] ; Samuli Ripatti [Finlande, Royaume-Uni] ; Nancy L. Pedersen [Suède] ; Inga Prokopenko [Royaume-Uni] ; Mark I. Mccarthy [Royaume-Uni] ; Erik Ingelsson [Suède, Royaume-Uni]

Source :

RBID : PMC:4407863

Descripteurs français

English descriptors

Abstract

Observational studies have reported different effects of adiposity on cardiovascular risk factors across age and sex. Since cardiovascular risk factors are enriched in obese individuals, it has not been easy to dissect the effects of adiposity from those of other risk factors. We used a Mendelian randomization approach, applying a set of 32 genetic markers to estimate the causal effect of adiposity on blood pressure, glycemic indices, circulating lipid levels, and markers of inflammation and liver disease in up to 67,553 individuals. All analyses were stratified by age (cutoff 55 years of age) and sex. The genetic score was associated with BMI in both nonstratified analysis (P = 2.8 × 10−107) and stratified analyses (all P < 3.3 × 10−30). We found evidence of a causal effect of adiposity on blood pressure, fasting levels of insulin, C-reactive protein, interleukin-6, HDL cholesterol, and triglycerides in a nonstratified analysis and in the <55-year stratum. Further, we found evidence of a smaller causal effect on total cholesterol (P for difference = 0.015) in the ≥55-year stratum than in the <55-year stratum, a finding that could be explained by biology, survival bias, or differential medication. In conclusion, this study extends previous knowledge of the effects of adiposity by providing sex- and age-specific causal estimates on cardiovascular risk factors.


Url:
DOI: 10.2337/db14-0988
PubMed: 25712996
PubMed Central: 4407863


Affiliations:

Links toward previous steps (curation, corpus...)

Le document en format XML

<record>
<TEI>
<teiHeader>
<fileDesc>
<titleStmt>
<title xml:lang="en">Age- and Sex-Specific Causal Effects of Adiposity on Cardiovascular Risk Factors</title>
<author>
<name sortKey="Fall, Tove" sort="Fall, Tove" uniqKey="Fall T" first="Tove" last="Fall">Tove Fall</name>
<affiliation wicri:level="4">
<nlm:aff id="aff1">Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala</wicri:regionArea>
<orgName type="university">Université d'Uppsala</orgName>
<placeName>
<settlement type="city">Uppsala</settlement>
<region nuts="1">Svealand</region>
<region nuts="1">East Middle Sweden</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="H Gg, Sara" sort="H Gg, Sara" uniqKey="H Gg S" first="Sara" last="H Gg">Sara H Gg</name>
<affiliation wicri:level="4">
<nlm:aff id="aff1">Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala</wicri:regionArea>
<orgName type="university">Université d'Uppsala</orgName>
<placeName>
<settlement type="city">Uppsala</settlement>
<region nuts="1">Svealand</region>
<region nuts="1">East Middle Sweden</region>
</placeName>
</affiliation>
<affiliation wicri:level="3">
<nlm:aff id="aff2">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea>
<placeName>
<settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Ploner, Alexander" sort="Ploner, Alexander" uniqKey="Ploner A" first="Alexander" last="Ploner">Alexander Ploner</name>
<affiliation wicri:level="3">
<nlm:aff id="aff2">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea>
<placeName>
<settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="M Gi, Reedik" sort="M Gi, Reedik" uniqKey="M Gi R" first="Reedik" last="M Gi">Reedik M Gi</name>
<affiliation wicri:level="1">
<nlm:aff id="aff3">Estonian Genome Center, University of Tartu, Tartu, Estonia</nlm:aff>
<country xml:lang="fr">Estonie</country>
<wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea>
<wicri:noRegion>Tartu</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Fischer, Krista" sort="Fischer, Krista" uniqKey="Fischer K" first="Krista" last="Fischer">Krista Fischer</name>
<affiliation wicri:level="1">
<nlm:aff id="aff3">Estonian Genome Center, University of Tartu, Tartu, Estonia</nlm:aff>
<country xml:lang="fr">Estonie</country>
<wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea>
<wicri:noRegion>Tartu</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Draisma, Harmen H M" sort="Draisma, Harmen H M" uniqKey="Draisma H" first="Harmen H. M." last="Draisma">Harmen H. M. Draisma</name>
<affiliation wicri:level="3">
<nlm:aff id="aff4">Department of Biological Psychology, VU University Amsterdam, Amsterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Biological Psychology, VU University Amsterdam, Amsterdam</wicri:regionArea>
<placeName>
<settlement type="city">Amsterdam</settlement>
<region nuts="2" type="province">Hollande-Septentrionale</region>
</placeName>
</affiliation>
<affiliation wicri:level="3">
<nlm:aff id="aff5">The EMGO Institute for Health and Care Research, Amsterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>The EMGO Institute for Health and Care Research, Amsterdam</wicri:regionArea>
<placeName>
<settlement type="city">Amsterdam</settlement>
<region nuts="2" type="province">Hollande-Septentrionale</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Sarin, Antti Pekka" sort="Sarin, Antti Pekka" uniqKey="Sarin A" first="Antti-Pekka" last="Sarin">Antti-Pekka Sarin</name>
<affiliation wicri:level="4">
<nlm:aff id="aff6">Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki</wicri:regionArea>
<orgName type="university">Université d'Helsinki</orgName>
<placeName>
<settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff7">Public Health Genomics Unit, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Public Health Genomics Unit, National Institute for Health and Welfare, Helsinki</wicri:regionArea>
<wicri:noRegion>Helsinki</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Benyamin, Beben" sort="Benyamin, Beben" uniqKey="Benyamin B" first="Beben" last="Benyamin">Beben Benyamin</name>
<affiliation wicri:level="1">
<nlm:aff id="aff8">Queensland Brain Institute, University of Queensland, St. Lucia, Queensland, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Queensland Brain Institute, University of Queensland, St. Lucia, Queensland</wicri:regionArea>
<wicri:noRegion>Queensland</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff9">QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>QIMR Berghofer Medical Research Institute, Brisbane, Queensland</wicri:regionArea>
<wicri:noRegion>Queensland</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Ladenvall, Claes" sort="Ladenvall, Claes" uniqKey="Ladenvall C" first="Claes" last="Ladenvall">Claes Ladenvall</name>
<affiliation wicri:level="1">
<nlm:aff id="aff10">Department of Clinical Sciences, Diabetes and Endocrinology, Skåne University Hospital, Lund University, Malmö, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Clinical Sciences, Diabetes and Endocrinology, Skåne University Hospital, Lund University, Malmö</wicri:regionArea>
<wicri:noRegion>Malmö</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey=" Kerlund, Mikael" sort=" Kerlund, Mikael" uniqKey=" Kerlund M" first="Mikael" last=" Kerlund">Mikael Kerlund</name>
<affiliation wicri:level="1">
<nlm:aff id="aff10">Department of Clinical Sciences, Diabetes and Endocrinology, Skåne University Hospital, Lund University, Malmö, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Clinical Sciences, Diabetes and Endocrinology, Skåne University Hospital, Lund University, Malmö</wicri:regionArea>
<wicri:noRegion>Malmö</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Kals, Mart" sort="Kals, Mart" uniqKey="Kals M" first="Mart" last="Kals">Mart Kals</name>
<affiliation wicri:level="1">
<nlm:aff id="aff3">Estonian Genome Center, University of Tartu, Tartu, Estonia</nlm:aff>
<country xml:lang="fr">Estonie</country>
<wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea>
<wicri:noRegion>Tartu</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff11">Institute of Mathematical Statistics, University of Tartu, Tartu, Estonia</nlm:aff>
<country xml:lang="fr">Estonie</country>
<wicri:regionArea>Institute of Mathematical Statistics, University of Tartu, Tartu</wicri:regionArea>
<wicri:noRegion>Tartu</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Esko, T Nu" sort="Esko, T Nu" uniqKey="Esko T" first="T Nu" last="Esko">T Nu Esko</name>
<affiliation wicri:level="1">
<nlm:aff id="aff3">Estonian Genome Center, University of Tartu, Tartu, Estonia</nlm:aff>
<country xml:lang="fr">Estonie</country>
<wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea>
<wicri:noRegion>Tartu</wicri:noRegion>
</affiliation>
<affiliation wicri:level="2">
<nlm:aff id="aff12">Division of Endocrinology, Children's Hospital Boston, Boston, MA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>Division of Endocrinology, Children's Hospital Boston, Boston</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2">
<nlm:aff id="aff13">Department of Genetics, Harvard Medical School, Boston, MA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>Department of Genetics, Harvard Medical School, Boston</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2">
<nlm:aff id="aff14">The Broad Institute, Massachusetts Institute of Technology/Harvard University, Cambridge, MA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>The Broad Institute, Massachusetts Institute of Technology/Harvard University, Cambridge</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Nelson, Christopher P" sort="Nelson, Christopher P" uniqKey="Nelson C" first="Christopher P." last="Nelson">Christopher P. Nelson</name>
<affiliation wicri:level="1">
<nlm:aff id="aff15">Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, National Institute for Health Research, Leicester, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, National Institute for Health Research, Leicester</wicri:regionArea>
<wicri:noRegion>Leicester</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff16">Department of Cardiovascular Sciences, University of Leicester, BHF Cardiovascular Research Centre, Glenfield Hospital, Leicester, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Cardiovascular Sciences, University of Leicester, BHF Cardiovascular Research Centre, Glenfield Hospital, Leicester</wicri:regionArea>
<wicri:noRegion>Leicester</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Kaakinen, Marika" sort="Kaakinen, Marika" uniqKey="Kaakinen M" first="Marika" last="Kaakinen">Marika Kaakinen</name>
<affiliation wicri:level="1">
<nlm:aff id="aff17">Institute of Health Sciences and Biocenter Oulu, University of Oulu, Oulu, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute of Health Sciences and Biocenter Oulu, University of Oulu, Oulu</wicri:regionArea>
<wicri:noRegion>Oulu</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Huikari, Ville" sort="Huikari, Ville" uniqKey="Huikari V" first="Ville" last="Huikari">Ville Huikari</name>
<affiliation wicri:level="1">
<nlm:aff id="aff18">Institute of Health Sciences, University of Oulu, Oulu, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute of Health Sciences, University of Oulu, Oulu</wicri:regionArea>
<wicri:noRegion>Oulu</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Mangino, Massimo" sort="Mangino, Massimo" uniqKey="Mangino M" first="Massimo" last="Mangino">Massimo Mangino</name>
<affiliation wicri:level="3">
<nlm:aff id="aff19">Department of Twin Research and Genetic Epidemiology, King's College London, London, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King's College London, London</wicri:regionArea>
<placeName>
<settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Meirhaeghe, Aline" sort="Meirhaeghe, Aline" uniqKey="Meirhaeghe A" first="Aline" last="Meirhaeghe">Aline Meirhaeghe</name>
<affiliation wicri:level="1">
<nlm:aff id="aff20">INSERM, U744, Institut Pasteur de Lille, Université Lille Nord de France, UDSL, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM, U744, Institut Pasteur de Lille, Université Lille Nord de France, UDSL</wicri:regionArea>
<wicri:noRegion>UDSL</wicri:noRegion>
<wicri:noRegion>UDSL</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Kristiansson, Kati" sort="Kristiansson, Kati" uniqKey="Kristiansson K" first="Kati" last="Kristiansson">Kati Kristiansson</name>
<affiliation wicri:level="1">
<nlm:aff id="aff21">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea>
<wicri:noRegion>Helsinki</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Nuotio, Marja Liisa" sort="Nuotio, Marja Liisa" uniqKey="Nuotio M" first="Marja-Liisa" last="Nuotio">Marja-Liisa Nuotio</name>
<affiliation wicri:level="1">
<nlm:aff id="aff21">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea>
<wicri:noRegion>Helsinki</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Kobl, Michael" sort="Kobl, Michael" uniqKey="Kobl M" first="Michael" last="Kobl">Michael Kobl</name>
<affiliation wicri:level="1">
<nlm:aff id="aff22">Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Grallert, Harald" sort="Grallert, Harald" uniqKey="Grallert H" first="Harald" last="Grallert">Harald Grallert</name>
<affiliation wicri:level="1">
<nlm:aff id="aff23">Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff24">Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff25">German Center for Diabetes Research, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Center for Diabetes Research, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Dehghan, Abbas" sort="Dehghan, Abbas" uniqKey="Dehghan A" first="Abbas" last="Dehghan">Abbas Dehghan</name>
<affiliation wicri:level="3">
<nlm:aff id="aff26">Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea>
<placeName>
<settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Kuningas, Maris" sort="Kuningas, Maris" uniqKey="Kuningas M" first="Maris" last="Kuningas">Maris Kuningas</name>
<affiliation wicri:level="3">
<nlm:aff id="aff26">Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea>
<placeName>
<settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff27">Inspectorate for Health Care, the Hague, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Inspectorate for Health Care, the Hague</wicri:regionArea>
<wicri:noRegion>the Hague</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="De Vries, Paul S" sort="De Vries, Paul S" uniqKey="De Vries P" first="Paul S." last="De Vries">Paul S. De Vries</name>
<affiliation wicri:level="3">
<nlm:aff id="aff26">Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea>
<placeName>
<settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="De Bruijn, Renee F A G" sort="De Bruijn, Renee F A G" uniqKey="De Bruijn R" first="Renée F. A. G." last="De Bruijn">Renée F. A. G. De Bruijn</name>
<affiliation wicri:level="3">
<nlm:aff id="aff26">Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea>
<placeName>
<settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
<affiliation wicri:level="3">
<nlm:aff id="aff28">Department of Neurology, Erasmus Medical Center, Rotterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Neurology, Erasmus Medical Center, Rotterdam</wicri:regionArea>
<placeName>
<settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Willems, Sara M" sort="Willems, Sara M" uniqKey="Willems S" first="Sara M." last="Willems">Sara M. Willems</name>
<affiliation wicri:level="3">
<nlm:aff id="aff26">Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea>
<placeName>
<settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Heikkil, Kauko" sort="Heikkil, Kauko" uniqKey="Heikkil K" first="Kauko" last="Heikkil">Kauko Heikkil</name>
<affiliation wicri:level="4">
<nlm:aff id="aff29">Department of Public Health, Hjelt Institute, University of Helsinki, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Public Health, Hjelt Institute, University of Helsinki, Helsinki</wicri:regionArea>
<orgName type="university">Université d'Helsinki</orgName>
<placeName>
<settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Silventoinen, Karri" sort="Silventoinen, Karri" uniqKey="Silventoinen K" first="Karri" last="Silventoinen">Karri Silventoinen</name>
<affiliation wicri:level="4">
<nlm:aff id="aff30">Department of Social Research, University of Helsinki, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Social Research, University of Helsinki, Helsinki</wicri:regionArea>
<orgName type="university">Université d'Helsinki</orgName>
<placeName>
<settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Pietil Inen, Kirsi H" sort="Pietil Inen, Kirsi H" uniqKey="Pietil Inen K" first="Kirsi H." last="Pietil Inen">Kirsi H. Pietil Inen</name>
<affiliation wicri:level="4">
<nlm:aff id="aff6">Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki</wicri:regionArea>
<orgName type="university">Université d'Helsinki</orgName>
<placeName>
<settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
</affiliation>
<affiliation wicri:level="4">
<nlm:aff id="aff31">Obesity Research Unit, Research Programs Unit, Diabetes and Obesity, University of Helsinki, Helsinki Finland</nlm:aff>
<orgName type="university">Université d'Helsinki</orgName>
<country>Finlande</country>
<placeName>
<settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff32">Department of Medicine, Division of Endocrinology, Helsinki University Central Hospital, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Medicine, Division of Endocrinology, Helsinki University Central Hospital</wicri:regionArea>
<wicri:noRegion>Helsinki University Central Hospital</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Legry, Vanessa" sort="Legry, Vanessa" uniqKey="Legry V" first="Vanessa" last="Legry">Vanessa Legry</name>
<affiliation wicri:level="1">
<nlm:aff id="aff20">INSERM, U744, Institut Pasteur de Lille, Université Lille Nord de France, UDSL, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM, U744, Institut Pasteur de Lille, Université Lille Nord de France, UDSL</wicri:regionArea>
<wicri:noRegion>UDSL</wicri:noRegion>
<wicri:noRegion>UDSL</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Giedraitis, Vilmantas" sort="Giedraitis, Vilmantas" uniqKey="Giedraitis V" first="Vilmantas" last="Giedraitis">Vilmantas Giedraitis</name>
<affiliation wicri:level="4">
<nlm:aff id="aff33">Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Public Health and Caring Sciences, Uppsala University, Uppsala</wicri:regionArea>
<orgName type="university">Université d'Uppsala</orgName>
<placeName>
<settlement type="city">Uppsala</settlement>
<region nuts="1">Svealand</region>
<region nuts="1">East Middle Sweden</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Goumidi, Louisa" sort="Goumidi, Louisa" uniqKey="Goumidi L" first="Louisa" last="Goumidi">Louisa Goumidi</name>
<affiliation wicri:level="1">
<nlm:aff id="aff20">INSERM, U744, Institut Pasteur de Lille, Université Lille Nord de France, UDSL, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM, U744, Institut Pasteur de Lille, Université Lille Nord de France, UDSL</wicri:regionArea>
<wicri:noRegion>UDSL</wicri:noRegion>
<wicri:noRegion>UDSL</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Syv Nen, Ann Christine" sort="Syv Nen, Ann Christine" uniqKey="Syv Nen A" first="Ann-Christine" last="Syv Nen">Ann-Christine Syv Nen</name>
<affiliation wicri:level="4">
<nlm:aff id="aff34">Department of Medical Sciences, Uppsala University, Uppsala, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medical Sciences, Uppsala University, Uppsala</wicri:regionArea>
<orgName type="university">Université d'Uppsala</orgName>
<placeName>
<settlement type="city">Uppsala</settlement>
<region nuts="1">Svealand</region>
<region nuts="1">East Middle Sweden</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Strauch, Konstantin" sort="Strauch, Konstantin" uniqKey="Strauch K" first="Konstantin" last="Strauch">Konstantin Strauch</name>
<affiliation wicri:level="1">
<nlm:aff id="aff22">Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
<affiliation wicri:level="3">
<nlm:aff id="aff35">Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität, Munich</wicri:regionArea>
<placeName>
<region type="land" nuts="1">Bavière</region>
<region type="district" nuts="2">District de Haute-Bavière</region>
<settlement type="city">Munich</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Koenig, Wolfgang" sort="Koenig, Wolfgang" uniqKey="Koenig W" first="Wolfgang" last="Koenig">Wolfgang Koenig</name>
<affiliation wicri:level="3">
<nlm:aff id="aff36">Department of Internal Medicine II-Cardiology, University of Ulm Medical Center, Ulm, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Internal Medicine II-Cardiology, University of Ulm Medical Center, Ulm</wicri:regionArea>
<placeName>
<region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Tübingen</region>
<settlement type="city">Ulm</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Lichtner, Peter" sort="Lichtner, Peter" uniqKey="Lichtner P" first="Peter" last="Lichtner">Peter Lichtner</name>
<affiliation wicri:level="1">
<nlm:aff id="aff37">Institut für Humangenetik, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institut für Humangenetik, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Herder, Christian" sort="Herder, Christian" uniqKey="Herder C" first="Christian" last="Herder">Christian Herder</name>
<affiliation wicri:level="3">
<nlm:aff id="aff38">Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf</wicri:regionArea>
<placeName>
<region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region>
<region type="district" nuts="2">District de Düsseldorf</region>
<settlement type="city">Düsseldorf</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff39">German Center for Diabetes Research, partner Düsseldorf, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Center for Diabetes Research, partner Düsseldorf</wicri:regionArea>
<wicri:noRegion>partner Düsseldorf</wicri:noRegion>
<wicri:noRegion>partner Düsseldorf</wicri:noRegion>
<wicri:noRegion>partner Düsseldorf</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Palotie, Aarno" sort="Palotie, Aarno" uniqKey="Palotie A" first="Aarno" last="Palotie">Aarno Palotie</name>
<affiliation wicri:level="4">
<nlm:aff id="aff6">Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki</wicri:regionArea>
<orgName type="university">Université d'Helsinki</orgName>
<placeName>
<settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff7">Public Health Genomics Unit, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Public Health Genomics Unit, National Institute for Health and Welfare, Helsinki</wicri:regionArea>
<wicri:noRegion>Helsinki</wicri:noRegion>
</affiliation>
<affiliation wicri:level="2">
<nlm:aff id="aff14">The Broad Institute, Massachusetts Institute of Technology/Harvard University, Cambridge, MA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>The Broad Institute, Massachusetts Institute of Technology/Harvard University, Cambridge</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Menni, Cristina" sort="Menni, Cristina" uniqKey="Menni C" first="Cristina" last="Menni">Cristina Menni</name>
<affiliation wicri:level="3">
<nlm:aff id="aff19">Department of Twin Research and Genetic Epidemiology, King's College London, London, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King's College London, London</wicri:regionArea>
<placeName>
<settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="André G." last="Uitterlinden">André G. Uitterlinden</name>
<affiliation wicri:level="3">
<nlm:aff id="aff26">Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea>
<placeName>
<settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
<affiliation>
<nlm:aff id="aff40">Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherland</nlm:aff>
<wicri:noCountry code="subfield">the Netherland</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Kuulasmaa, Kari" sort="Kuulasmaa, Kari" uniqKey="Kuulasmaa K" first="Kari" last="Kuulasmaa">Kari Kuulasmaa</name>
<affiliation wicri:level="1">
<nlm:aff id="aff21">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea>
<wicri:noRegion>Helsinki</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Havulinna, Aki S" sort="Havulinna, Aki S" uniqKey="Havulinna A" first="Aki S." last="Havulinna">Aki S. Havulinna</name>
<affiliation wicri:level="1">
<nlm:aff id="aff21">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea>
<wicri:noRegion>Helsinki</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Moreno, Luis A" sort="Moreno, Luis A" uniqKey="Moreno L" first="Luis A." last="Moreno">Luis A. Moreno</name>
<affiliation wicri:level="1">
<nlm:aff id="aff41">Growth, Exercise, Nutrition and Development Research Group, Department of Physiatry and Nursery, Faculty of Health Sciences, University of Zaragoza, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Growth, Exercise, Nutrition and Development Research Group, Department of Physiatry and Nursery, Faculty of Health Sciences, University of Zaragoza</wicri:regionArea>
<wicri:noRegion>University of Zaragoza</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Gonzalez Gross, Marcela" sort="Gonzalez Gross, Marcela" uniqKey="Gonzalez Gross M" first="Marcela" last="Gonzalez-Gross">Marcela Gonzalez-Gross</name>
<affiliation wicri:level="3">
<nlm:aff id="aff42">ImFine Research Group, Departamento de Salud y Rendimiento Humano, Facultad de Ciencias de la Actividad Física y del Deporte, Universidad Politécnica de Madrid, Madrid, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>ImFine Research Group, Departamento de Salud y Rendimiento Humano, Facultad de Ciencias de la Actividad Física y del Deporte, Universidad Politécnica de Madrid, Madrid</wicri:regionArea>
<placeName>
<settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Evans, Alun" sort="Evans, Alun" uniqKey="Evans A" first="Alun" last="Evans">Alun Evans</name>
<affiliation wicri:level="1">
<nlm:aff id="aff43">Centre for Public Health, the Queen's University of Belfast, Belfast, Northern Ireland, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Centre for Public Health, the Queen's University of Belfast, Belfast, Northern Ireland</wicri:regionArea>
<wicri:noRegion>Northern Ireland</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Tregouet, David Alexandre" sort="Tregouet, David Alexandre" uniqKey="Tregouet D" first="David-Alexandre" last="Tregouet">David-Alexandre Tregouet</name>
<affiliation wicri:level="3">
<nlm:aff id="aff44">Team Genomics & Pathophysiology of Cardiovascular Diseases, Sorbonne Universités, Université Pierre et Marie Curie of Paris 06, UMRS 1166, Paris, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Team Genomics & Pathophysiology of Cardiovascular Diseases, Sorbonne Universités, Université Pierre et Marie Curie of Paris 06, UMRS 1166, Paris</wicri:regionArea>
<placeName>
<region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3">
<nlm:aff id="aff45">Team Genomics & Pathophysiology of Cardiovascular Diseases, INSERM, UMRS 1166, Paris, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Team Genomics & Pathophysiology of Cardiovascular Diseases, INSERM, UMRS 1166, Paris</wicri:regionArea>
<placeName>
<region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3">
<nlm:aff id="aff46">Institute for Cardiometabolism and Nutrition, Paris, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Institute for Cardiometabolism and Nutrition, Paris</wicri:regionArea>
<placeName>
<region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Yarnell, John W G" sort="Yarnell, John W G" uniqKey="Yarnell J" first="John W. G." last="Yarnell">John W. G. Yarnell</name>
<affiliation wicri:level="1">
<nlm:aff id="aff43">Centre for Public Health, the Queen's University of Belfast, Belfast, Northern Ireland, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Centre for Public Health, the Queen's University of Belfast, Belfast, Northern Ireland</wicri:regionArea>
<wicri:noRegion>Northern Ireland</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Virtamo, Jarmo" sort="Virtamo, Jarmo" uniqKey="Virtamo J" first="Jarmo" last="Virtamo">Jarmo Virtamo</name>
<affiliation wicri:level="1">
<nlm:aff id="aff21">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea>
<wicri:noRegion>Helsinki</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Ferrieres, Jean" sort="Ferrieres, Jean" uniqKey="Ferrieres J" first="Jean" last="Ferrières">Jean Ferrières</name>
<affiliation wicri:level="3">
<nlm:aff id="aff47">Department of Cardiology, Toulouse University School of Medicine, Rangueil Hospital, Toulouse, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Cardiology, Toulouse University School of Medicine, Rangueil Hospital, Toulouse</wicri:regionArea>
<placeName>
<region type="region">Occitanie (région administrative)</region>
<region type="old region">Midi-Pyrénées</region>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Veronesi, Giovanni" sort="Veronesi, Giovanni" uniqKey="Veronesi G" first="Giovanni" last="Veronesi">Giovanni Veronesi</name>
<affiliation wicri:level="1">
<nlm:aff id="aff48">Research Center on Epidemiology and Preventive Medicine, Department of Clinical and Experimental Medicine, University of Insubria, Varese, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Research Center on Epidemiology and Preventive Medicine, Department of Clinical and Experimental Medicine, University of Insubria, Varese</wicri:regionArea>
<wicri:noRegion>Varese</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Perola, Markus" sort="Perola, Markus" uniqKey="Perola M" first="Markus" last="Perola">Markus Perola</name>
<affiliation wicri:level="1">
<nlm:aff id="aff21">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea>
<wicri:noRegion>Helsinki</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Arveiler, Dominique" sort="Arveiler, Dominique" uniqKey="Arveiler D" first="Dominique" last="Arveiler">Dominique Arveiler</name>
<affiliation wicri:level="3">
<nlm:aff id="aff49">Department of Epidemiology and Public Health, University of Strasbourg and University Hospital of Strasbourg, Strasbourg, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Epidemiology and Public Health, University of Strasbourg and University Hospital of Strasbourg, Strasbourg</wicri:regionArea>
<placeName>
<region type="region">Grand Est</region>
<region type="old region">Alsace (région administrative)</region>
<settlement type="city">Strasbourg</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Brambilla, Paolo" sort="Brambilla, Paolo" uniqKey="Brambilla P" first="Paolo" last="Brambilla">Paolo Brambilla</name>
<affiliation wicri:level="1">
<nlm:aff id="aff50">Department of Experimental Medicine, University of Milano-Bicocca, Monza, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Experimental Medicine, University of Milano-Bicocca, Monza</wicri:regionArea>
<wicri:noRegion>Monza</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Lind, Lars" sort="Lind, Lars" uniqKey="Lind L" first="Lars" last="Lind">Lars Lind</name>
<affiliation wicri:level="4">
<nlm:aff id="aff34">Department of Medical Sciences, Uppsala University, Uppsala, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medical Sciences, Uppsala University, Uppsala</wicri:regionArea>
<orgName type="university">Université d'Uppsala</orgName>
<placeName>
<settlement type="city">Uppsala</settlement>
<region nuts="1">Svealand</region>
<region nuts="1">East Middle Sweden</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Kaprio, Jaakko" sort="Kaprio, Jaakko" uniqKey="Kaprio J" first="Jaakko" last="Kaprio">Jaakko Kaprio</name>
<affiliation wicri:level="4">
<nlm:aff id="aff6">Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki</wicri:regionArea>
<orgName type="university">Université d'Helsinki</orgName>
<placeName>
<settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
</affiliation>
<affiliation wicri:level="4">
<nlm:aff id="aff29">Department of Public Health, Hjelt Institute, University of Helsinki, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Public Health, Hjelt Institute, University of Helsinki, Helsinki</wicri:regionArea>
<orgName type="university">Université d'Helsinki</orgName>
<placeName>
<settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff51">National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>National Institute for Health and Welfare, Helsinki</wicri:regionArea>
<wicri:noRegion>Helsinki</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name>
<affiliation wicri:level="3">
<nlm:aff id="aff26">Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea>
<placeName>
<settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Stricker, Bruno H" sort="Stricker, Bruno H" uniqKey="Stricker B" first="Bruno H." last="Stricker">Bruno H. Stricker</name>
<affiliation wicri:level="3">
<nlm:aff id="aff26">Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea>
<placeName>
<settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff27">Inspectorate for Health Care, the Hague, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Inspectorate for Health Care, the Hague</wicri:regionArea>
<wicri:noRegion>the Hague</wicri:noRegion>
</affiliation>
<affiliation>
<nlm:aff id="aff40">Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherland</nlm:aff>
<wicri:noCountry code="subfield">the Netherland</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Van Duijn, Cornelia M" sort="Van Duijn, Cornelia M" uniqKey="Van Duijn C" first="Cornelia M." last="Van Duijn">Cornelia M. Van Duijn</name>
<affiliation wicri:level="3">
<nlm:aff id="aff26">Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea>
<placeName>
<settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Ikram, M Arfan" sort="Ikram, M Arfan" uniqKey="Ikram M" first="M. Arfan" last="Ikram">M. Arfan Ikram</name>
<affiliation wicri:level="3">
<nlm:aff id="aff26">Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea>
<placeName>
<settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
<affiliation wicri:level="3">
<nlm:aff id="aff28">Department of Neurology, Erasmus Medical Center, Rotterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Neurology, Erasmus Medical Center, Rotterdam</wicri:regionArea>
<placeName>
<settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Franco, Oscar H" sort="Franco, Oscar H" uniqKey="Franco O" first="Oscar H." last="Franco">Oscar H. Franco</name>
<affiliation wicri:level="3">
<nlm:aff id="aff26">Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea>
<placeName>
<settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Cottel, Dominique" sort="Cottel, Dominique" uniqKey="Cottel D" first="Dominique" last="Cottel">Dominique Cottel</name>
<affiliation wicri:level="1">
<nlm:aff id="aff20">INSERM, U744, Institut Pasteur de Lille, Université Lille Nord de France, UDSL, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM, U744, Institut Pasteur de Lille, Université Lille Nord de France, UDSL</wicri:regionArea>
<wicri:noRegion>UDSL</wicri:noRegion>
<wicri:noRegion>UDSL</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Dallongeville, Jean" sort="Dallongeville, Jean" uniqKey="Dallongeville J" first="Jean" last="Dallongeville">Jean Dallongeville</name>
<affiliation wicri:level="1">
<nlm:aff id="aff20">INSERM, U744, Institut Pasteur de Lille, Université Lille Nord de France, UDSL, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM, U744, Institut Pasteur de Lille, Université Lille Nord de France, UDSL</wicri:regionArea>
<wicri:noRegion>UDSL</wicri:noRegion>
<wicri:noRegion>UDSL</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Hall, Alistair S" sort="Hall, Alistair S" uniqKey="Hall A" first="Alistair S." last="Hall">Alistair S. Hall</name>
<affiliation wicri:level="4">
<nlm:aff id="aff52">Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, Leeds, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, Leeds</wicri:regionArea>
<orgName type="university">Université de Leeds</orgName>
<placeName>
<settlement type="city">Leeds</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Yorkshire-et-Humber</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Jula, Antti" sort="Jula, Antti" uniqKey="Jula A" first="Antti" last="Jula">Antti Jula</name>
<affiliation wicri:level="3">
<nlm:aff id="aff53">Population Studies Unit, Department of Chronic Disease Prevention, National Institute for Health and Welfare, Turku, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Population Studies Unit, Department of Chronic Disease Prevention, National Institute for Health and Welfare, Turku</wicri:regionArea>
<placeName>
<settlement type="city">Turku</settlement>
<region type="région" nuts="2">Finlande occidentale</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Tobin, Martin D" sort="Tobin, Martin D" uniqKey="Tobin M" first="Martin D." last="Tobin">Martin D. Tobin</name>
<affiliation wicri:level="1">
<nlm:aff id="aff54">Department of Health Sciences and Genetics, University of Leicester, Leicester, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Health Sciences and Genetics, University of Leicester, Leicester</wicri:regionArea>
<wicri:noRegion>Leicester</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Penninx, Brenda W" sort="Penninx, Brenda W" uniqKey="Penninx B" first="Brenda W." last="Penninx">Brenda W. Penninx</name>
<affiliation wicri:level="3">
<nlm:aff id="aff5">The EMGO Institute for Health and Care Research, Amsterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>The EMGO Institute for Health and Care Research, Amsterdam</wicri:regionArea>
<placeName>
<settlement type="city">Amsterdam</settlement>
<region nuts="2" type="province">Hollande-Septentrionale</region>
</placeName>
</affiliation>
<affiliation wicri:level="3">
<nlm:aff id="aff55">Department of Psychiatry, VU University Medical Center, Amsterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Psychiatry, VU University Medical Center, Amsterdam</wicri:regionArea>
<placeName>
<settlement type="city">Amsterdam</settlement>
<region nuts="2" type="province">Hollande-Septentrionale</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Peters, Annette" sort="Peters, Annette" uniqKey="Peters A" first="Annette" last="Peters">Annette Peters</name>
<affiliation wicri:level="1">
<nlm:aff id="aff24">Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name>
<affiliation wicri:level="1">
<nlm:aff id="aff22">Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff23">Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff24">Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Samani, Nilesh J" sort="Samani, Nilesh J" uniqKey="Samani N" first="Nilesh J." last="Samani">Nilesh J. Samani</name>
<affiliation wicri:level="1">
<nlm:aff id="aff15">Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, National Institute for Health Research, Leicester, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, National Institute for Health Research, Leicester</wicri:regionArea>
<wicri:noRegion>Leicester</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff16">Department of Cardiovascular Sciences, University of Leicester, BHF Cardiovascular Research Centre, Glenfield Hospital, Leicester, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Cardiovascular Sciences, University of Leicester, BHF Cardiovascular Research Centre, Glenfield Hospital, Leicester</wicri:regionArea>
<wicri:noRegion>Leicester</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Montgomery, Grant W" sort="Montgomery, Grant W" uniqKey="Montgomery G" first="Grant W." last="Montgomery">Grant W. Montgomery</name>
<affiliation wicri:level="1">
<nlm:aff id="aff9">QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>QIMR Berghofer Medical Research Institute, Brisbane, Queensland</wicri:regionArea>
<wicri:noRegion>Queensland</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Whitfield, John B" sort="Whitfield, John B" uniqKey="Whitfield J" first="John B." last="Whitfield">John B. Whitfield</name>
<affiliation wicri:level="1">
<nlm:aff id="aff9">QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>QIMR Berghofer Medical Research Institute, Brisbane, Queensland</wicri:regionArea>
<wicri:noRegion>Queensland</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Martin, Nicholas G" sort="Martin, Nicholas G" uniqKey="Martin N" first="Nicholas G." last="Martin">Nicholas G. Martin</name>
<affiliation wicri:level="1">
<nlm:aff id="aff9">QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>QIMR Berghofer Medical Research Institute, Brisbane, Queensland</wicri:regionArea>
<wicri:noRegion>Queensland</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Groop, Leif" sort="Groop, Leif" uniqKey="Groop L" first="Leif" last="Groop">Leif Groop</name>
<affiliation wicri:level="4">
<nlm:aff id="aff6">Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki</wicri:regionArea>
<orgName type="university">Université d'Helsinki</orgName>
<placeName>
<settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff10">Department of Clinical Sciences, Diabetes and Endocrinology, Skåne University Hospital, Lund University, Malmö, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Clinical Sciences, Diabetes and Endocrinology, Skåne University Hospital, Lund University, Malmö</wicri:regionArea>
<wicri:noRegion>Malmö</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Spector, Tim D" sort="Spector, Tim D" uniqKey="Spector T" first="Tim D." last="Spector">Tim D. Spector</name>
<affiliation wicri:level="3">
<nlm:aff id="aff19">Department of Twin Research and Genetic Epidemiology, King's College London, London, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King's College London, London</wicri:regionArea>
<placeName>
<settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Magnusson, Patrik K" sort="Magnusson, Patrik K" uniqKey="Magnusson P" first="Patrik K." last="Magnusson">Patrik K. Magnusson</name>
<affiliation wicri:level="3">
<nlm:aff id="aff2">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea>
<placeName>
<settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Amouyel, Philippe" sort="Amouyel, Philippe" uniqKey="Amouyel P" first="Philippe" last="Amouyel">Philippe Amouyel</name>
<affiliation wicri:level="1">
<nlm:aff id="aff20">INSERM, U744, Institut Pasteur de Lille, Université Lille Nord de France, UDSL, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM, U744, Institut Pasteur de Lille, Université Lille Nord de France, UDSL</wicri:regionArea>
<wicri:noRegion>UDSL</wicri:noRegion>
<wicri:noRegion>UDSL</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Boomsma, Dorret I" sort="Boomsma, Dorret I" uniqKey="Boomsma D" first="Dorret I." last="Boomsma">Dorret I. Boomsma</name>
<affiliation wicri:level="3">
<nlm:aff id="aff4">Department of Biological Psychology, VU University Amsterdam, Amsterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Biological Psychology, VU University Amsterdam, Amsterdam</wicri:regionArea>
<placeName>
<settlement type="city">Amsterdam</settlement>
<region nuts="2" type="province">Hollande-Septentrionale</region>
</placeName>
</affiliation>
<affiliation wicri:level="3">
<nlm:aff id="aff5">The EMGO Institute for Health and Care Research, Amsterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>The EMGO Institute for Health and Care Research, Amsterdam</wicri:regionArea>
<placeName>
<settlement type="city">Amsterdam</settlement>
<region nuts="2" type="province">Hollande-Septentrionale</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Nilsson, Peter M" sort="Nilsson, Peter M" uniqKey="Nilsson P" first="Peter M." last="Nilsson">Peter M. Nilsson</name>
<affiliation wicri:level="1">
<nlm:aff id="aff56">Department of Clinical Sciences, Lund University, Malmö, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Clinical Sciences, Lund University, Malmö</wicri:regionArea>
<wicri:noRegion>Malmö</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="J Rvelin, Marjo Riitta" sort="J Rvelin, Marjo Riitta" uniqKey="J Rvelin M" first="Marjo-Riitta" last="J Rvelin">Marjo-Riitta J Rvelin</name>
<affiliation wicri:level="1">
<nlm:aff id="aff17">Institute of Health Sciences and Biocenter Oulu, University of Oulu, Oulu, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute of Health Sciences and Biocenter Oulu, University of Oulu, Oulu</wicri:regionArea>
<wicri:noRegion>Oulu</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff57">Department of Children, Young People and Families, National Institute for Health and Welfare, Oulu, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Children, Young People and Families, National Institute for Health and Welfare, Oulu</wicri:regionArea>
<wicri:noRegion>Oulu</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff58">Department of Epidemiology and Biostatistics, Medical Research Council Health Protection Agency, Centre for Environment & Health, School of Public Health, Imperial College London, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Epidemiology and Biostatistics, Medical Research Council Health Protection Agency, Centre for Environment & Health, School of Public Health, Imperial College London</wicri:regionArea>
<wicri:noRegion>Imperial College London</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff59">Unit of Primary Care, Oulu University Hospital, Oulu, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Unit of Primary Care, Oulu University Hospital, Oulu</wicri:regionArea>
<wicri:noRegion>Oulu</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Lyssenko, Valeriya" sort="Lyssenko, Valeriya" uniqKey="Lyssenko V" first="Valeriya" last="Lyssenko">Valeriya Lyssenko</name>
<affiliation wicri:level="1">
<nlm:aff id="aff10">Department of Clinical Sciences, Diabetes and Endocrinology, Skåne University Hospital, Lund University, Malmö, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Clinical Sciences, Diabetes and Endocrinology, Skåne University Hospital, Lund University, Malmö</wicri:regionArea>
<wicri:noRegion>Malmö</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff60">Steno Diabetes Center, Gentofte, Denmark</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>Steno Diabetes Center, Gentofte</wicri:regionArea>
<wicri:noRegion>Gentofte</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Metspalu, Andres" sort="Metspalu, Andres" uniqKey="Metspalu A" first="Andres" last="Metspalu">Andres Metspalu</name>
<affiliation wicri:level="1">
<nlm:aff id="aff3">Estonian Genome Center, University of Tartu, Tartu, Estonia</nlm:aff>
<country xml:lang="fr">Estonie</country>
<wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea>
<wicri:noRegion>Tartu</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Strachan, David P" sort="Strachan, David P" uniqKey="Strachan D" first="David P." last="Strachan">David P. Strachan</name>
<affiliation wicri:level="4">
<nlm:aff id="aff61">St. George's, University of London, London, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>St. George's, University of London, London</wicri:regionArea>
<placeName>
<settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
<settlement type="city">Londres</settlement>
</placeName>
<orgName type="university">Université de Londres</orgName>
</affiliation>
</author>
<author>
<name sortKey="Salomaa, Veikko" sort="Salomaa, Veikko" uniqKey="Salomaa V" first="Veikko" last="Salomaa">Veikko Salomaa</name>
<affiliation wicri:level="1">
<nlm:aff id="aff21">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea>
<wicri:noRegion>Helsinki</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Ripatti, Samuli" sort="Ripatti, Samuli" uniqKey="Ripatti S" first="Samuli" last="Ripatti">Samuli Ripatti</name>
<affiliation wicri:level="4">
<nlm:aff id="aff6">Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki</wicri:regionArea>
<orgName type="university">Université d'Helsinki</orgName>
<placeName>
<settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff7">Public Health Genomics Unit, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Public Health Genomics Unit, National Institute for Health and Welfare, Helsinki</wicri:regionArea>
<wicri:noRegion>Helsinki</wicri:noRegion>
</affiliation>
<affiliation wicri:level="4">
<nlm:aff id="aff29">Department of Public Health, Hjelt Institute, University of Helsinki, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Public Health, Hjelt Institute, University of Helsinki, Helsinki</wicri:regionArea>
<orgName type="university">Université d'Helsinki</orgName>
<placeName>
<settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
</affiliation>
<affiliation wicri:level="4">
<nlm:aff id="aff62">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea>
<placeName>
<settlement type="city">Oxford</settlement>
<region type="country">Angleterre</region>
<region type="comté" nuts="2">Oxfordshire</region>
<settlement type="city">Oxford</settlement>
</placeName>
<orgName type="university">Université d'Oxford</orgName>
</affiliation>
</author>
<author>
<name sortKey="Pedersen, Nancy L" sort="Pedersen, Nancy L" uniqKey="Pedersen N" first="Nancy L." last="Pedersen">Nancy L. Pedersen</name>
<affiliation wicri:level="3">
<nlm:aff id="aff2">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea>
<placeName>
<settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Prokopenko, Inga" sort="Prokopenko, Inga" uniqKey="Prokopenko I" first="Inga" last="Prokopenko">Inga Prokopenko</name>
<affiliation wicri:level="4">
<nlm:aff id="aff62">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea>
<placeName>
<settlement type="city">Oxford</settlement>
<region type="country">Angleterre</region>
<region type="comté" nuts="2">Oxfordshire</region>
<settlement type="city">Oxford</settlement>
</placeName>
<orgName type="university">Université d'Oxford</orgName>
</affiliation>
<affiliation wicri:level="3">
<nlm:aff id="aff63">Department of Genomics of Common Disease, School of Public Health, Imperial College London, London, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Genomics of Common Disease, School of Public Health, Imperial College London, London</wicri:regionArea>
<placeName>
<settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
<affiliation wicri:level="4">
<nlm:aff id="aff64">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford</wicri:regionArea>
<placeName>
<settlement type="city">Oxford</settlement>
<region type="country">Angleterre</region>
<region type="comté" nuts="2">Oxfordshire</region>
<settlement type="city">Oxford</settlement>
</placeName>
<orgName type="university">Université d'Oxford</orgName>
</affiliation>
</author>
<author>
<name sortKey="Mccarthy, Mark I" sort="Mccarthy, Mark I" uniqKey="Mccarthy M" first="Mark I." last="Mccarthy">Mark I. Mccarthy</name>
<affiliation wicri:level="4">
<nlm:aff id="aff62">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea>
<placeName>
<settlement type="city">Oxford</settlement>
<region type="country">Angleterre</region>
<region type="comté" nuts="2">Oxfordshire</region>
<settlement type="city">Oxford</settlement>
</placeName>
<orgName type="university">Université d'Oxford</orgName>
</affiliation>
<affiliation wicri:level="4">
<nlm:aff id="aff64">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford</wicri:regionArea>
<placeName>
<settlement type="city">Oxford</settlement>
<region type="country">Angleterre</region>
<region type="comté" nuts="2">Oxfordshire</region>
<settlement type="city">Oxford</settlement>
</placeName>
<orgName type="university">Université d'Oxford</orgName>
</affiliation>
<affiliation wicri:level="3">
<nlm:aff id="aff65">Oxford National Institute for Health Research Biomedical Research Centre, Churchill Hospital, Oxford, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Oxford National Institute for Health Research Biomedical Research Centre, Churchill Hospital, Oxford</wicri:regionArea>
<placeName>
<settlement type="city">Oxford</settlement>
<region type="country">Angleterre</region>
<region type="comté" nuts="2">Oxfordshire</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Ingelsson, Erik" sort="Ingelsson, Erik" uniqKey="Ingelsson E" first="Erik" last="Ingelsson">Erik Ingelsson</name>
<affiliation wicri:level="4">
<nlm:aff id="aff1">Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala</wicri:regionArea>
<orgName type="university">Université d'Uppsala</orgName>
<placeName>
<settlement type="city">Uppsala</settlement>
<region nuts="1">Svealand</region>
<region nuts="1">East Middle Sweden</region>
</placeName>
</affiliation>
<affiliation wicri:level="4">
<nlm:aff id="aff62">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea>
<placeName>
<settlement type="city">Oxford</settlement>
<region type="country">Angleterre</region>
<region type="comté" nuts="2">Oxfordshire</region>
<settlement type="city">Oxford</settlement>
</placeName>
<orgName type="university">Université d'Oxford</orgName>
</affiliation>
</author>
</titleStmt>
<publicationStmt>
<idno type="wicri:source">PMC</idno>
<idno type="pmid">25712996</idno>
<idno type="pmc">4407863</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407863</idno>
<idno type="RBID">PMC:4407863</idno>
<idno type="doi">10.2337/db14-0988</idno>
<date when="2015">2015</date>
<idno type="wicri:Area/Pmc/Corpus">002423</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002423</idno>
<idno type="wicri:Area/Pmc/Curation">002273</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002273</idno>
<idno type="wicri:Area/Pmc/Checkpoint">001199</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">001199</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="wicri:Area/PubMed/Corpus">002E10</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002E10</idno>
<idno type="wicri:Area/PubMed/Curation">002D34</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002D34</idno>
<idno type="wicri:Area/PubMed/Checkpoint">002D34</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002D34</idno>
<idno type="wicri:Area/Ncbi/Merge">002290</idno>
<idno type="wicri:Area/Ncbi/Curation">002290</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">002290</idno>
<idno type="wicri:doubleKey">0012-1797:2015:Fall T:age:and:sex</idno>
<idno type="wicri:Area/Main/Merge">003203</idno>
<idno type="wicri:Area/Main/Curation">003202</idno>
<idno type="wicri:Area/Main/Exploration">003202</idno>
</publicationStmt>
<sourceDesc>
<biblStruct>
<analytic>
<title xml:lang="en" level="a" type="main">Age- and Sex-Specific Causal Effects of Adiposity on Cardiovascular Risk Factors</title>
<author>
<name sortKey="Fall, Tove" sort="Fall, Tove" uniqKey="Fall T" first="Tove" last="Fall">Tove Fall</name>
<affiliation wicri:level="4">
<nlm:aff id="aff1">Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala</wicri:regionArea>
<orgName type="university">Université d'Uppsala</orgName>
<placeName>
<settlement type="city">Uppsala</settlement>
<region nuts="1">Svealand</region>
<region nuts="1">East Middle Sweden</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="H Gg, Sara" sort="H Gg, Sara" uniqKey="H Gg S" first="Sara" last="H Gg">Sara H Gg</name>
<affiliation wicri:level="4">
<nlm:aff id="aff1">Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala</wicri:regionArea>
<orgName type="university">Université d'Uppsala</orgName>
<placeName>
<settlement type="city">Uppsala</settlement>
<region nuts="1">Svealand</region>
<region nuts="1">East Middle Sweden</region>
</placeName>
</affiliation>
<affiliation wicri:level="3">
<nlm:aff id="aff2">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea>
<placeName>
<settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Ploner, Alexander" sort="Ploner, Alexander" uniqKey="Ploner A" first="Alexander" last="Ploner">Alexander Ploner</name>
<affiliation wicri:level="3">
<nlm:aff id="aff2">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea>
<placeName>
<settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="M Gi, Reedik" sort="M Gi, Reedik" uniqKey="M Gi R" first="Reedik" last="M Gi">Reedik M Gi</name>
<affiliation wicri:level="1">
<nlm:aff id="aff3">Estonian Genome Center, University of Tartu, Tartu, Estonia</nlm:aff>
<country xml:lang="fr">Estonie</country>
<wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea>
<wicri:noRegion>Tartu</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Fischer, Krista" sort="Fischer, Krista" uniqKey="Fischer K" first="Krista" last="Fischer">Krista Fischer</name>
<affiliation wicri:level="1">
<nlm:aff id="aff3">Estonian Genome Center, University of Tartu, Tartu, Estonia</nlm:aff>
<country xml:lang="fr">Estonie</country>
<wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea>
<wicri:noRegion>Tartu</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Draisma, Harmen H M" sort="Draisma, Harmen H M" uniqKey="Draisma H" first="Harmen H. M." last="Draisma">Harmen H. M. Draisma</name>
<affiliation wicri:level="3">
<nlm:aff id="aff4">Department of Biological Psychology, VU University Amsterdam, Amsterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Biological Psychology, VU University Amsterdam, Amsterdam</wicri:regionArea>
<placeName>
<settlement type="city">Amsterdam</settlement>
<region nuts="2" type="province">Hollande-Septentrionale</region>
</placeName>
</affiliation>
<affiliation wicri:level="3">
<nlm:aff id="aff5">The EMGO Institute for Health and Care Research, Amsterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>The EMGO Institute for Health and Care Research, Amsterdam</wicri:regionArea>
<placeName>
<settlement type="city">Amsterdam</settlement>
<region nuts="2" type="province">Hollande-Septentrionale</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Sarin, Antti Pekka" sort="Sarin, Antti Pekka" uniqKey="Sarin A" first="Antti-Pekka" last="Sarin">Antti-Pekka Sarin</name>
<affiliation wicri:level="4">
<nlm:aff id="aff6">Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki</wicri:regionArea>
<orgName type="university">Université d'Helsinki</orgName>
<placeName>
<settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff7">Public Health Genomics Unit, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Public Health Genomics Unit, National Institute for Health and Welfare, Helsinki</wicri:regionArea>
<wicri:noRegion>Helsinki</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Benyamin, Beben" sort="Benyamin, Beben" uniqKey="Benyamin B" first="Beben" last="Benyamin">Beben Benyamin</name>
<affiliation wicri:level="1">
<nlm:aff id="aff8">Queensland Brain Institute, University of Queensland, St. Lucia, Queensland, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Queensland Brain Institute, University of Queensland, St. Lucia, Queensland</wicri:regionArea>
<wicri:noRegion>Queensland</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff9">QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>QIMR Berghofer Medical Research Institute, Brisbane, Queensland</wicri:regionArea>
<wicri:noRegion>Queensland</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Ladenvall, Claes" sort="Ladenvall, Claes" uniqKey="Ladenvall C" first="Claes" last="Ladenvall">Claes Ladenvall</name>
<affiliation wicri:level="1">
<nlm:aff id="aff10">Department of Clinical Sciences, Diabetes and Endocrinology, Skåne University Hospital, Lund University, Malmö, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Clinical Sciences, Diabetes and Endocrinology, Skåne University Hospital, Lund University, Malmö</wicri:regionArea>
<wicri:noRegion>Malmö</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey=" Kerlund, Mikael" sort=" Kerlund, Mikael" uniqKey=" Kerlund M" first="Mikael" last=" Kerlund">Mikael Kerlund</name>
<affiliation wicri:level="1">
<nlm:aff id="aff10">Department of Clinical Sciences, Diabetes and Endocrinology, Skåne University Hospital, Lund University, Malmö, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Clinical Sciences, Diabetes and Endocrinology, Skåne University Hospital, Lund University, Malmö</wicri:regionArea>
<wicri:noRegion>Malmö</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Kals, Mart" sort="Kals, Mart" uniqKey="Kals M" first="Mart" last="Kals">Mart Kals</name>
<affiliation wicri:level="1">
<nlm:aff id="aff3">Estonian Genome Center, University of Tartu, Tartu, Estonia</nlm:aff>
<country xml:lang="fr">Estonie</country>
<wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea>
<wicri:noRegion>Tartu</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff11">Institute of Mathematical Statistics, University of Tartu, Tartu, Estonia</nlm:aff>
<country xml:lang="fr">Estonie</country>
<wicri:regionArea>Institute of Mathematical Statistics, University of Tartu, Tartu</wicri:regionArea>
<wicri:noRegion>Tartu</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Esko, T Nu" sort="Esko, T Nu" uniqKey="Esko T" first="T Nu" last="Esko">T Nu Esko</name>
<affiliation wicri:level="1">
<nlm:aff id="aff3">Estonian Genome Center, University of Tartu, Tartu, Estonia</nlm:aff>
<country xml:lang="fr">Estonie</country>
<wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea>
<wicri:noRegion>Tartu</wicri:noRegion>
</affiliation>
<affiliation wicri:level="2">
<nlm:aff id="aff12">Division of Endocrinology, Children's Hospital Boston, Boston, MA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>Division of Endocrinology, Children's Hospital Boston, Boston</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2">
<nlm:aff id="aff13">Department of Genetics, Harvard Medical School, Boston, MA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>Department of Genetics, Harvard Medical School, Boston</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2">
<nlm:aff id="aff14">The Broad Institute, Massachusetts Institute of Technology/Harvard University, Cambridge, MA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>The Broad Institute, Massachusetts Institute of Technology/Harvard University, Cambridge</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Nelson, Christopher P" sort="Nelson, Christopher P" uniqKey="Nelson C" first="Christopher P." last="Nelson">Christopher P. Nelson</name>
<affiliation wicri:level="1">
<nlm:aff id="aff15">Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, National Institute for Health Research, Leicester, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, National Institute for Health Research, Leicester</wicri:regionArea>
<wicri:noRegion>Leicester</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff16">Department of Cardiovascular Sciences, University of Leicester, BHF Cardiovascular Research Centre, Glenfield Hospital, Leicester, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Cardiovascular Sciences, University of Leicester, BHF Cardiovascular Research Centre, Glenfield Hospital, Leicester</wicri:regionArea>
<wicri:noRegion>Leicester</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Kaakinen, Marika" sort="Kaakinen, Marika" uniqKey="Kaakinen M" first="Marika" last="Kaakinen">Marika Kaakinen</name>
<affiliation wicri:level="1">
<nlm:aff id="aff17">Institute of Health Sciences and Biocenter Oulu, University of Oulu, Oulu, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute of Health Sciences and Biocenter Oulu, University of Oulu, Oulu</wicri:regionArea>
<wicri:noRegion>Oulu</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Huikari, Ville" sort="Huikari, Ville" uniqKey="Huikari V" first="Ville" last="Huikari">Ville Huikari</name>
<affiliation wicri:level="1">
<nlm:aff id="aff18">Institute of Health Sciences, University of Oulu, Oulu, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute of Health Sciences, University of Oulu, Oulu</wicri:regionArea>
<wicri:noRegion>Oulu</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Mangino, Massimo" sort="Mangino, Massimo" uniqKey="Mangino M" first="Massimo" last="Mangino">Massimo Mangino</name>
<affiliation wicri:level="3">
<nlm:aff id="aff19">Department of Twin Research and Genetic Epidemiology, King's College London, London, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King's College London, London</wicri:regionArea>
<placeName>
<settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Meirhaeghe, Aline" sort="Meirhaeghe, Aline" uniqKey="Meirhaeghe A" first="Aline" last="Meirhaeghe">Aline Meirhaeghe</name>
<affiliation wicri:level="1">
<nlm:aff id="aff20">INSERM, U744, Institut Pasteur de Lille, Université Lille Nord de France, UDSL, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM, U744, Institut Pasteur de Lille, Université Lille Nord de France, UDSL</wicri:regionArea>
<wicri:noRegion>UDSL</wicri:noRegion>
<wicri:noRegion>UDSL</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Kristiansson, Kati" sort="Kristiansson, Kati" uniqKey="Kristiansson K" first="Kati" last="Kristiansson">Kati Kristiansson</name>
<affiliation wicri:level="1">
<nlm:aff id="aff21">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea>
<wicri:noRegion>Helsinki</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Nuotio, Marja Liisa" sort="Nuotio, Marja Liisa" uniqKey="Nuotio M" first="Marja-Liisa" last="Nuotio">Marja-Liisa Nuotio</name>
<affiliation wicri:level="1">
<nlm:aff id="aff21">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea>
<wicri:noRegion>Helsinki</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Kobl, Michael" sort="Kobl, Michael" uniqKey="Kobl M" first="Michael" last="Kobl">Michael Kobl</name>
<affiliation wicri:level="1">
<nlm:aff id="aff22">Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Grallert, Harald" sort="Grallert, Harald" uniqKey="Grallert H" first="Harald" last="Grallert">Harald Grallert</name>
<affiliation wicri:level="1">
<nlm:aff id="aff23">Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff24">Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff25">German Center for Diabetes Research, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Center for Diabetes Research, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Dehghan, Abbas" sort="Dehghan, Abbas" uniqKey="Dehghan A" first="Abbas" last="Dehghan">Abbas Dehghan</name>
<affiliation wicri:level="3">
<nlm:aff id="aff26">Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea>
<placeName>
<settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Kuningas, Maris" sort="Kuningas, Maris" uniqKey="Kuningas M" first="Maris" last="Kuningas">Maris Kuningas</name>
<affiliation wicri:level="3">
<nlm:aff id="aff26">Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea>
<placeName>
<settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff27">Inspectorate for Health Care, the Hague, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Inspectorate for Health Care, the Hague</wicri:regionArea>
<wicri:noRegion>the Hague</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="De Vries, Paul S" sort="De Vries, Paul S" uniqKey="De Vries P" first="Paul S." last="De Vries">Paul S. De Vries</name>
<affiliation wicri:level="3">
<nlm:aff id="aff26">Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea>
<placeName>
<settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="De Bruijn, Renee F A G" sort="De Bruijn, Renee F A G" uniqKey="De Bruijn R" first="Renée F. A. G." last="De Bruijn">Renée F. A. G. De Bruijn</name>
<affiliation wicri:level="3">
<nlm:aff id="aff26">Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea>
<placeName>
<settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
<affiliation wicri:level="3">
<nlm:aff id="aff28">Department of Neurology, Erasmus Medical Center, Rotterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Neurology, Erasmus Medical Center, Rotterdam</wicri:regionArea>
<placeName>
<settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Willems, Sara M" sort="Willems, Sara M" uniqKey="Willems S" first="Sara M." last="Willems">Sara M. Willems</name>
<affiliation wicri:level="3">
<nlm:aff id="aff26">Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea>
<placeName>
<settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Heikkil, Kauko" sort="Heikkil, Kauko" uniqKey="Heikkil K" first="Kauko" last="Heikkil">Kauko Heikkil</name>
<affiliation wicri:level="4">
<nlm:aff id="aff29">Department of Public Health, Hjelt Institute, University of Helsinki, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Public Health, Hjelt Institute, University of Helsinki, Helsinki</wicri:regionArea>
<orgName type="university">Université d'Helsinki</orgName>
<placeName>
<settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Silventoinen, Karri" sort="Silventoinen, Karri" uniqKey="Silventoinen K" first="Karri" last="Silventoinen">Karri Silventoinen</name>
<affiliation wicri:level="4">
<nlm:aff id="aff30">Department of Social Research, University of Helsinki, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Social Research, University of Helsinki, Helsinki</wicri:regionArea>
<orgName type="university">Université d'Helsinki</orgName>
<placeName>
<settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Pietil Inen, Kirsi H" sort="Pietil Inen, Kirsi H" uniqKey="Pietil Inen K" first="Kirsi H." last="Pietil Inen">Kirsi H. Pietil Inen</name>
<affiliation wicri:level="4">
<nlm:aff id="aff6">Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki</wicri:regionArea>
<orgName type="university">Université d'Helsinki</orgName>
<placeName>
<settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
</affiliation>
<affiliation wicri:level="4">
<nlm:aff id="aff31">Obesity Research Unit, Research Programs Unit, Diabetes and Obesity, University of Helsinki, Helsinki Finland</nlm:aff>
<orgName type="university">Université d'Helsinki</orgName>
<country>Finlande</country>
<placeName>
<settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff32">Department of Medicine, Division of Endocrinology, Helsinki University Central Hospital, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Medicine, Division of Endocrinology, Helsinki University Central Hospital</wicri:regionArea>
<wicri:noRegion>Helsinki University Central Hospital</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Legry, Vanessa" sort="Legry, Vanessa" uniqKey="Legry V" first="Vanessa" last="Legry">Vanessa Legry</name>
<affiliation wicri:level="1">
<nlm:aff id="aff20">INSERM, U744, Institut Pasteur de Lille, Université Lille Nord de France, UDSL, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM, U744, Institut Pasteur de Lille, Université Lille Nord de France, UDSL</wicri:regionArea>
<wicri:noRegion>UDSL</wicri:noRegion>
<wicri:noRegion>UDSL</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Giedraitis, Vilmantas" sort="Giedraitis, Vilmantas" uniqKey="Giedraitis V" first="Vilmantas" last="Giedraitis">Vilmantas Giedraitis</name>
<affiliation wicri:level="4">
<nlm:aff id="aff33">Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Public Health and Caring Sciences, Uppsala University, Uppsala</wicri:regionArea>
<orgName type="university">Université d'Uppsala</orgName>
<placeName>
<settlement type="city">Uppsala</settlement>
<region nuts="1">Svealand</region>
<region nuts="1">East Middle Sweden</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Goumidi, Louisa" sort="Goumidi, Louisa" uniqKey="Goumidi L" first="Louisa" last="Goumidi">Louisa Goumidi</name>
<affiliation wicri:level="1">
<nlm:aff id="aff20">INSERM, U744, Institut Pasteur de Lille, Université Lille Nord de France, UDSL, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM, U744, Institut Pasteur de Lille, Université Lille Nord de France, UDSL</wicri:regionArea>
<wicri:noRegion>UDSL</wicri:noRegion>
<wicri:noRegion>UDSL</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Syv Nen, Ann Christine" sort="Syv Nen, Ann Christine" uniqKey="Syv Nen A" first="Ann-Christine" last="Syv Nen">Ann-Christine Syv Nen</name>
<affiliation wicri:level="4">
<nlm:aff id="aff34">Department of Medical Sciences, Uppsala University, Uppsala, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medical Sciences, Uppsala University, Uppsala</wicri:regionArea>
<orgName type="university">Université d'Uppsala</orgName>
<placeName>
<settlement type="city">Uppsala</settlement>
<region nuts="1">Svealand</region>
<region nuts="1">East Middle Sweden</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Strauch, Konstantin" sort="Strauch, Konstantin" uniqKey="Strauch K" first="Konstantin" last="Strauch">Konstantin Strauch</name>
<affiliation wicri:level="1">
<nlm:aff id="aff22">Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
<affiliation wicri:level="3">
<nlm:aff id="aff35">Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität, Munich</wicri:regionArea>
<placeName>
<region type="land" nuts="1">Bavière</region>
<region type="district" nuts="2">District de Haute-Bavière</region>
<settlement type="city">Munich</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Koenig, Wolfgang" sort="Koenig, Wolfgang" uniqKey="Koenig W" first="Wolfgang" last="Koenig">Wolfgang Koenig</name>
<affiliation wicri:level="3">
<nlm:aff id="aff36">Department of Internal Medicine II-Cardiology, University of Ulm Medical Center, Ulm, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Internal Medicine II-Cardiology, University of Ulm Medical Center, Ulm</wicri:regionArea>
<placeName>
<region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Tübingen</region>
<settlement type="city">Ulm</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Lichtner, Peter" sort="Lichtner, Peter" uniqKey="Lichtner P" first="Peter" last="Lichtner">Peter Lichtner</name>
<affiliation wicri:level="1">
<nlm:aff id="aff37">Institut für Humangenetik, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institut für Humangenetik, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Herder, Christian" sort="Herder, Christian" uniqKey="Herder C" first="Christian" last="Herder">Christian Herder</name>
<affiliation wicri:level="3">
<nlm:aff id="aff38">Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf</wicri:regionArea>
<placeName>
<region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region>
<region type="district" nuts="2">District de Düsseldorf</region>
<settlement type="city">Düsseldorf</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff39">German Center for Diabetes Research, partner Düsseldorf, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Center for Diabetes Research, partner Düsseldorf</wicri:regionArea>
<wicri:noRegion>partner Düsseldorf</wicri:noRegion>
<wicri:noRegion>partner Düsseldorf</wicri:noRegion>
<wicri:noRegion>partner Düsseldorf</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Palotie, Aarno" sort="Palotie, Aarno" uniqKey="Palotie A" first="Aarno" last="Palotie">Aarno Palotie</name>
<affiliation wicri:level="4">
<nlm:aff id="aff6">Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki</wicri:regionArea>
<orgName type="university">Université d'Helsinki</orgName>
<placeName>
<settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff7">Public Health Genomics Unit, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Public Health Genomics Unit, National Institute for Health and Welfare, Helsinki</wicri:regionArea>
<wicri:noRegion>Helsinki</wicri:noRegion>
</affiliation>
<affiliation wicri:level="2">
<nlm:aff id="aff14">The Broad Institute, Massachusetts Institute of Technology/Harvard University, Cambridge, MA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>The Broad Institute, Massachusetts Institute of Technology/Harvard University, Cambridge</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Menni, Cristina" sort="Menni, Cristina" uniqKey="Menni C" first="Cristina" last="Menni">Cristina Menni</name>
<affiliation wicri:level="3">
<nlm:aff id="aff19">Department of Twin Research and Genetic Epidemiology, King's College London, London, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King's College London, London</wicri:regionArea>
<placeName>
<settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="André G." last="Uitterlinden">André G. Uitterlinden</name>
<affiliation wicri:level="3">
<nlm:aff id="aff26">Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea>
<placeName>
<settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
<affiliation>
<nlm:aff id="aff40">Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherland</nlm:aff>
<wicri:noCountry code="subfield">the Netherland</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Kuulasmaa, Kari" sort="Kuulasmaa, Kari" uniqKey="Kuulasmaa K" first="Kari" last="Kuulasmaa">Kari Kuulasmaa</name>
<affiliation wicri:level="1">
<nlm:aff id="aff21">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea>
<wicri:noRegion>Helsinki</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Havulinna, Aki S" sort="Havulinna, Aki S" uniqKey="Havulinna A" first="Aki S." last="Havulinna">Aki S. Havulinna</name>
<affiliation wicri:level="1">
<nlm:aff id="aff21">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea>
<wicri:noRegion>Helsinki</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Moreno, Luis A" sort="Moreno, Luis A" uniqKey="Moreno L" first="Luis A." last="Moreno">Luis A. Moreno</name>
<affiliation wicri:level="1">
<nlm:aff id="aff41">Growth, Exercise, Nutrition and Development Research Group, Department of Physiatry and Nursery, Faculty of Health Sciences, University of Zaragoza, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Growth, Exercise, Nutrition and Development Research Group, Department of Physiatry and Nursery, Faculty of Health Sciences, University of Zaragoza</wicri:regionArea>
<wicri:noRegion>University of Zaragoza</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Gonzalez Gross, Marcela" sort="Gonzalez Gross, Marcela" uniqKey="Gonzalez Gross M" first="Marcela" last="Gonzalez-Gross">Marcela Gonzalez-Gross</name>
<affiliation wicri:level="3">
<nlm:aff id="aff42">ImFine Research Group, Departamento de Salud y Rendimiento Humano, Facultad de Ciencias de la Actividad Física y del Deporte, Universidad Politécnica de Madrid, Madrid, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>ImFine Research Group, Departamento de Salud y Rendimiento Humano, Facultad de Ciencias de la Actividad Física y del Deporte, Universidad Politécnica de Madrid, Madrid</wicri:regionArea>
<placeName>
<settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Evans, Alun" sort="Evans, Alun" uniqKey="Evans A" first="Alun" last="Evans">Alun Evans</name>
<affiliation wicri:level="1">
<nlm:aff id="aff43">Centre for Public Health, the Queen's University of Belfast, Belfast, Northern Ireland, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Centre for Public Health, the Queen's University of Belfast, Belfast, Northern Ireland</wicri:regionArea>
<wicri:noRegion>Northern Ireland</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Tregouet, David Alexandre" sort="Tregouet, David Alexandre" uniqKey="Tregouet D" first="David-Alexandre" last="Tregouet">David-Alexandre Tregouet</name>
<affiliation wicri:level="3">
<nlm:aff id="aff44">Team Genomics & Pathophysiology of Cardiovascular Diseases, Sorbonne Universités, Université Pierre et Marie Curie of Paris 06, UMRS 1166, Paris, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Team Genomics & Pathophysiology of Cardiovascular Diseases, Sorbonne Universités, Université Pierre et Marie Curie of Paris 06, UMRS 1166, Paris</wicri:regionArea>
<placeName>
<region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3">
<nlm:aff id="aff45">Team Genomics & Pathophysiology of Cardiovascular Diseases, INSERM, UMRS 1166, Paris, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Team Genomics & Pathophysiology of Cardiovascular Diseases, INSERM, UMRS 1166, Paris</wicri:regionArea>
<placeName>
<region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3">
<nlm:aff id="aff46">Institute for Cardiometabolism and Nutrition, Paris, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Institute for Cardiometabolism and Nutrition, Paris</wicri:regionArea>
<placeName>
<region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Yarnell, John W G" sort="Yarnell, John W G" uniqKey="Yarnell J" first="John W. G." last="Yarnell">John W. G. Yarnell</name>
<affiliation wicri:level="1">
<nlm:aff id="aff43">Centre for Public Health, the Queen's University of Belfast, Belfast, Northern Ireland, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Centre for Public Health, the Queen's University of Belfast, Belfast, Northern Ireland</wicri:regionArea>
<wicri:noRegion>Northern Ireland</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Virtamo, Jarmo" sort="Virtamo, Jarmo" uniqKey="Virtamo J" first="Jarmo" last="Virtamo">Jarmo Virtamo</name>
<affiliation wicri:level="1">
<nlm:aff id="aff21">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea>
<wicri:noRegion>Helsinki</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Ferrieres, Jean" sort="Ferrieres, Jean" uniqKey="Ferrieres J" first="Jean" last="Ferrières">Jean Ferrières</name>
<affiliation wicri:level="3">
<nlm:aff id="aff47">Department of Cardiology, Toulouse University School of Medicine, Rangueil Hospital, Toulouse, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Cardiology, Toulouse University School of Medicine, Rangueil Hospital, Toulouse</wicri:regionArea>
<placeName>
<region type="region">Occitanie (région administrative)</region>
<region type="old region">Midi-Pyrénées</region>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Veronesi, Giovanni" sort="Veronesi, Giovanni" uniqKey="Veronesi G" first="Giovanni" last="Veronesi">Giovanni Veronesi</name>
<affiliation wicri:level="1">
<nlm:aff id="aff48">Research Center on Epidemiology and Preventive Medicine, Department of Clinical and Experimental Medicine, University of Insubria, Varese, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Research Center on Epidemiology and Preventive Medicine, Department of Clinical and Experimental Medicine, University of Insubria, Varese</wicri:regionArea>
<wicri:noRegion>Varese</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Perola, Markus" sort="Perola, Markus" uniqKey="Perola M" first="Markus" last="Perola">Markus Perola</name>
<affiliation wicri:level="1">
<nlm:aff id="aff21">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea>
<wicri:noRegion>Helsinki</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Arveiler, Dominique" sort="Arveiler, Dominique" uniqKey="Arveiler D" first="Dominique" last="Arveiler">Dominique Arveiler</name>
<affiliation wicri:level="3">
<nlm:aff id="aff49">Department of Epidemiology and Public Health, University of Strasbourg and University Hospital of Strasbourg, Strasbourg, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Epidemiology and Public Health, University of Strasbourg and University Hospital of Strasbourg, Strasbourg</wicri:regionArea>
<placeName>
<region type="region">Grand Est</region>
<region type="old region">Alsace (région administrative)</region>
<settlement type="city">Strasbourg</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Brambilla, Paolo" sort="Brambilla, Paolo" uniqKey="Brambilla P" first="Paolo" last="Brambilla">Paolo Brambilla</name>
<affiliation wicri:level="1">
<nlm:aff id="aff50">Department of Experimental Medicine, University of Milano-Bicocca, Monza, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Experimental Medicine, University of Milano-Bicocca, Monza</wicri:regionArea>
<wicri:noRegion>Monza</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Lind, Lars" sort="Lind, Lars" uniqKey="Lind L" first="Lars" last="Lind">Lars Lind</name>
<affiliation wicri:level="4">
<nlm:aff id="aff34">Department of Medical Sciences, Uppsala University, Uppsala, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medical Sciences, Uppsala University, Uppsala</wicri:regionArea>
<orgName type="university">Université d'Uppsala</orgName>
<placeName>
<settlement type="city">Uppsala</settlement>
<region nuts="1">Svealand</region>
<region nuts="1">East Middle Sweden</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Kaprio, Jaakko" sort="Kaprio, Jaakko" uniqKey="Kaprio J" first="Jaakko" last="Kaprio">Jaakko Kaprio</name>
<affiliation wicri:level="4">
<nlm:aff id="aff6">Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki</wicri:regionArea>
<orgName type="university">Université d'Helsinki</orgName>
<placeName>
<settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
</affiliation>
<affiliation wicri:level="4">
<nlm:aff id="aff29">Department of Public Health, Hjelt Institute, University of Helsinki, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Public Health, Hjelt Institute, University of Helsinki, Helsinki</wicri:regionArea>
<orgName type="university">Université d'Helsinki</orgName>
<placeName>
<settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff51">National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>National Institute for Health and Welfare, Helsinki</wicri:regionArea>
<wicri:noRegion>Helsinki</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name>
<affiliation wicri:level="3">
<nlm:aff id="aff26">Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea>
<placeName>
<settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Stricker, Bruno H" sort="Stricker, Bruno H" uniqKey="Stricker B" first="Bruno H." last="Stricker">Bruno H. Stricker</name>
<affiliation wicri:level="3">
<nlm:aff id="aff26">Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea>
<placeName>
<settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff27">Inspectorate for Health Care, the Hague, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Inspectorate for Health Care, the Hague</wicri:regionArea>
<wicri:noRegion>the Hague</wicri:noRegion>
</affiliation>
<affiliation>
<nlm:aff id="aff40">Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherland</nlm:aff>
<wicri:noCountry code="subfield">the Netherland</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Van Duijn, Cornelia M" sort="Van Duijn, Cornelia M" uniqKey="Van Duijn C" first="Cornelia M." last="Van Duijn">Cornelia M. Van Duijn</name>
<affiliation wicri:level="3">
<nlm:aff id="aff26">Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea>
<placeName>
<settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Ikram, M Arfan" sort="Ikram, M Arfan" uniqKey="Ikram M" first="M. Arfan" last="Ikram">M. Arfan Ikram</name>
<affiliation wicri:level="3">
<nlm:aff id="aff26">Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea>
<placeName>
<settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
<affiliation wicri:level="3">
<nlm:aff id="aff28">Department of Neurology, Erasmus Medical Center, Rotterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Neurology, Erasmus Medical Center, Rotterdam</wicri:regionArea>
<placeName>
<settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Franco, Oscar H" sort="Franco, Oscar H" uniqKey="Franco O" first="Oscar H." last="Franco">Oscar H. Franco</name>
<affiliation wicri:level="3">
<nlm:aff id="aff26">Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea>
<placeName>
<settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Cottel, Dominique" sort="Cottel, Dominique" uniqKey="Cottel D" first="Dominique" last="Cottel">Dominique Cottel</name>
<affiliation wicri:level="1">
<nlm:aff id="aff20">INSERM, U744, Institut Pasteur de Lille, Université Lille Nord de France, UDSL, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM, U744, Institut Pasteur de Lille, Université Lille Nord de France, UDSL</wicri:regionArea>
<wicri:noRegion>UDSL</wicri:noRegion>
<wicri:noRegion>UDSL</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Dallongeville, Jean" sort="Dallongeville, Jean" uniqKey="Dallongeville J" first="Jean" last="Dallongeville">Jean Dallongeville</name>
<affiliation wicri:level="1">
<nlm:aff id="aff20">INSERM, U744, Institut Pasteur de Lille, Université Lille Nord de France, UDSL, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM, U744, Institut Pasteur de Lille, Université Lille Nord de France, UDSL</wicri:regionArea>
<wicri:noRegion>UDSL</wicri:noRegion>
<wicri:noRegion>UDSL</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Hall, Alistair S" sort="Hall, Alistair S" uniqKey="Hall A" first="Alistair S." last="Hall">Alistair S. Hall</name>
<affiliation wicri:level="4">
<nlm:aff id="aff52">Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, Leeds, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, Leeds</wicri:regionArea>
<orgName type="university">Université de Leeds</orgName>
<placeName>
<settlement type="city">Leeds</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Yorkshire-et-Humber</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Jula, Antti" sort="Jula, Antti" uniqKey="Jula A" first="Antti" last="Jula">Antti Jula</name>
<affiliation wicri:level="3">
<nlm:aff id="aff53">Population Studies Unit, Department of Chronic Disease Prevention, National Institute for Health and Welfare, Turku, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Population Studies Unit, Department of Chronic Disease Prevention, National Institute for Health and Welfare, Turku</wicri:regionArea>
<placeName>
<settlement type="city">Turku</settlement>
<region type="région" nuts="2">Finlande occidentale</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Tobin, Martin D" sort="Tobin, Martin D" uniqKey="Tobin M" first="Martin D." last="Tobin">Martin D. Tobin</name>
<affiliation wicri:level="1">
<nlm:aff id="aff54">Department of Health Sciences and Genetics, University of Leicester, Leicester, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Health Sciences and Genetics, University of Leicester, Leicester</wicri:regionArea>
<wicri:noRegion>Leicester</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Penninx, Brenda W" sort="Penninx, Brenda W" uniqKey="Penninx B" first="Brenda W." last="Penninx">Brenda W. Penninx</name>
<affiliation wicri:level="3">
<nlm:aff id="aff5">The EMGO Institute for Health and Care Research, Amsterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>The EMGO Institute for Health and Care Research, Amsterdam</wicri:regionArea>
<placeName>
<settlement type="city">Amsterdam</settlement>
<region nuts="2" type="province">Hollande-Septentrionale</region>
</placeName>
</affiliation>
<affiliation wicri:level="3">
<nlm:aff id="aff55">Department of Psychiatry, VU University Medical Center, Amsterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Psychiatry, VU University Medical Center, Amsterdam</wicri:regionArea>
<placeName>
<settlement type="city">Amsterdam</settlement>
<region nuts="2" type="province">Hollande-Septentrionale</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Peters, Annette" sort="Peters, Annette" uniqKey="Peters A" first="Annette" last="Peters">Annette Peters</name>
<affiliation wicri:level="1">
<nlm:aff id="aff24">Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name>
<affiliation wicri:level="1">
<nlm:aff id="aff22">Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff23">Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff24">Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Samani, Nilesh J" sort="Samani, Nilesh J" uniqKey="Samani N" first="Nilesh J." last="Samani">Nilesh J. Samani</name>
<affiliation wicri:level="1">
<nlm:aff id="aff15">Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, National Institute for Health Research, Leicester, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, National Institute for Health Research, Leicester</wicri:regionArea>
<wicri:noRegion>Leicester</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff16">Department of Cardiovascular Sciences, University of Leicester, BHF Cardiovascular Research Centre, Glenfield Hospital, Leicester, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Cardiovascular Sciences, University of Leicester, BHF Cardiovascular Research Centre, Glenfield Hospital, Leicester</wicri:regionArea>
<wicri:noRegion>Leicester</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Montgomery, Grant W" sort="Montgomery, Grant W" uniqKey="Montgomery G" first="Grant W." last="Montgomery">Grant W. Montgomery</name>
<affiliation wicri:level="1">
<nlm:aff id="aff9">QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>QIMR Berghofer Medical Research Institute, Brisbane, Queensland</wicri:regionArea>
<wicri:noRegion>Queensland</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Whitfield, John B" sort="Whitfield, John B" uniqKey="Whitfield J" first="John B." last="Whitfield">John B. Whitfield</name>
<affiliation wicri:level="1">
<nlm:aff id="aff9">QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>QIMR Berghofer Medical Research Institute, Brisbane, Queensland</wicri:regionArea>
<wicri:noRegion>Queensland</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Martin, Nicholas G" sort="Martin, Nicholas G" uniqKey="Martin N" first="Nicholas G." last="Martin">Nicholas G. Martin</name>
<affiliation wicri:level="1">
<nlm:aff id="aff9">QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>QIMR Berghofer Medical Research Institute, Brisbane, Queensland</wicri:regionArea>
<wicri:noRegion>Queensland</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Groop, Leif" sort="Groop, Leif" uniqKey="Groop L" first="Leif" last="Groop">Leif Groop</name>
<affiliation wicri:level="4">
<nlm:aff id="aff6">Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki</wicri:regionArea>
<orgName type="university">Université d'Helsinki</orgName>
<placeName>
<settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff10">Department of Clinical Sciences, Diabetes and Endocrinology, Skåne University Hospital, Lund University, Malmö, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Clinical Sciences, Diabetes and Endocrinology, Skåne University Hospital, Lund University, Malmö</wicri:regionArea>
<wicri:noRegion>Malmö</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Spector, Tim D" sort="Spector, Tim D" uniqKey="Spector T" first="Tim D." last="Spector">Tim D. Spector</name>
<affiliation wicri:level="3">
<nlm:aff id="aff19">Department of Twin Research and Genetic Epidemiology, King's College London, London, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King's College London, London</wicri:regionArea>
<placeName>
<settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Magnusson, Patrik K" sort="Magnusson, Patrik K" uniqKey="Magnusson P" first="Patrik K." last="Magnusson">Patrik K. Magnusson</name>
<affiliation wicri:level="3">
<nlm:aff id="aff2">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea>
<placeName>
<settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Amouyel, Philippe" sort="Amouyel, Philippe" uniqKey="Amouyel P" first="Philippe" last="Amouyel">Philippe Amouyel</name>
<affiliation wicri:level="1">
<nlm:aff id="aff20">INSERM, U744, Institut Pasteur de Lille, Université Lille Nord de France, UDSL, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM, U744, Institut Pasteur de Lille, Université Lille Nord de France, UDSL</wicri:regionArea>
<wicri:noRegion>UDSL</wicri:noRegion>
<wicri:noRegion>UDSL</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Boomsma, Dorret I" sort="Boomsma, Dorret I" uniqKey="Boomsma D" first="Dorret I." last="Boomsma">Dorret I. Boomsma</name>
<affiliation wicri:level="3">
<nlm:aff id="aff4">Department of Biological Psychology, VU University Amsterdam, Amsterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Biological Psychology, VU University Amsterdam, Amsterdam</wicri:regionArea>
<placeName>
<settlement type="city">Amsterdam</settlement>
<region nuts="2" type="province">Hollande-Septentrionale</region>
</placeName>
</affiliation>
<affiliation wicri:level="3">
<nlm:aff id="aff5">The EMGO Institute for Health and Care Research, Amsterdam, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>The EMGO Institute for Health and Care Research, Amsterdam</wicri:regionArea>
<placeName>
<settlement type="city">Amsterdam</settlement>
<region nuts="2" type="province">Hollande-Septentrionale</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Nilsson, Peter M" sort="Nilsson, Peter M" uniqKey="Nilsson P" first="Peter M." last="Nilsson">Peter M. Nilsson</name>
<affiliation wicri:level="1">
<nlm:aff id="aff56">Department of Clinical Sciences, Lund University, Malmö, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Clinical Sciences, Lund University, Malmö</wicri:regionArea>
<wicri:noRegion>Malmö</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="J Rvelin, Marjo Riitta" sort="J Rvelin, Marjo Riitta" uniqKey="J Rvelin M" first="Marjo-Riitta" last="J Rvelin">Marjo-Riitta J Rvelin</name>
<affiliation wicri:level="1">
<nlm:aff id="aff17">Institute of Health Sciences and Biocenter Oulu, University of Oulu, Oulu, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute of Health Sciences and Biocenter Oulu, University of Oulu, Oulu</wicri:regionArea>
<wicri:noRegion>Oulu</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff57">Department of Children, Young People and Families, National Institute for Health and Welfare, Oulu, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Children, Young People and Families, National Institute for Health and Welfare, Oulu</wicri:regionArea>
<wicri:noRegion>Oulu</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff58">Department of Epidemiology and Biostatistics, Medical Research Council Health Protection Agency, Centre for Environment & Health, School of Public Health, Imperial College London, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Epidemiology and Biostatistics, Medical Research Council Health Protection Agency, Centre for Environment & Health, School of Public Health, Imperial College London</wicri:regionArea>
<wicri:noRegion>Imperial College London</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff59">Unit of Primary Care, Oulu University Hospital, Oulu, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Unit of Primary Care, Oulu University Hospital, Oulu</wicri:regionArea>
<wicri:noRegion>Oulu</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Lyssenko, Valeriya" sort="Lyssenko, Valeriya" uniqKey="Lyssenko V" first="Valeriya" last="Lyssenko">Valeriya Lyssenko</name>
<affiliation wicri:level="1">
<nlm:aff id="aff10">Department of Clinical Sciences, Diabetes and Endocrinology, Skåne University Hospital, Lund University, Malmö, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Clinical Sciences, Diabetes and Endocrinology, Skåne University Hospital, Lund University, Malmö</wicri:regionArea>
<wicri:noRegion>Malmö</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff60">Steno Diabetes Center, Gentofte, Denmark</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>Steno Diabetes Center, Gentofte</wicri:regionArea>
<wicri:noRegion>Gentofte</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Metspalu, Andres" sort="Metspalu, Andres" uniqKey="Metspalu A" first="Andres" last="Metspalu">Andres Metspalu</name>
<affiliation wicri:level="1">
<nlm:aff id="aff3">Estonian Genome Center, University of Tartu, Tartu, Estonia</nlm:aff>
<country xml:lang="fr">Estonie</country>
<wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea>
<wicri:noRegion>Tartu</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Strachan, David P" sort="Strachan, David P" uniqKey="Strachan D" first="David P." last="Strachan">David P. Strachan</name>
<affiliation wicri:level="4">
<nlm:aff id="aff61">St. George's, University of London, London, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>St. George's, University of London, London</wicri:regionArea>
<placeName>
<settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
<settlement type="city">Londres</settlement>
</placeName>
<orgName type="university">Université de Londres</orgName>
</affiliation>
</author>
<author>
<name sortKey="Salomaa, Veikko" sort="Salomaa, Veikko" uniqKey="Salomaa V" first="Veikko" last="Salomaa">Veikko Salomaa</name>
<affiliation wicri:level="1">
<nlm:aff id="aff21">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea>
<wicri:noRegion>Helsinki</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Ripatti, Samuli" sort="Ripatti, Samuli" uniqKey="Ripatti S" first="Samuli" last="Ripatti">Samuli Ripatti</name>
<affiliation wicri:level="4">
<nlm:aff id="aff6">Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki</wicri:regionArea>
<orgName type="university">Université d'Helsinki</orgName>
<placeName>
<settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff7">Public Health Genomics Unit, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Public Health Genomics Unit, National Institute for Health and Welfare, Helsinki</wicri:regionArea>
<wicri:noRegion>Helsinki</wicri:noRegion>
</affiliation>
<affiliation wicri:level="4">
<nlm:aff id="aff29">Department of Public Health, Hjelt Institute, University of Helsinki, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Public Health, Hjelt Institute, University of Helsinki, Helsinki</wicri:regionArea>
<orgName type="university">Université d'Helsinki</orgName>
<placeName>
<settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
</affiliation>
<affiliation wicri:level="4">
<nlm:aff id="aff62">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea>
<placeName>
<settlement type="city">Oxford</settlement>
<region type="country">Angleterre</region>
<region type="comté" nuts="2">Oxfordshire</region>
<settlement type="city">Oxford</settlement>
</placeName>
<orgName type="university">Université d'Oxford</orgName>
</affiliation>
</author>
<author>
<name sortKey="Pedersen, Nancy L" sort="Pedersen, Nancy L" uniqKey="Pedersen N" first="Nancy L." last="Pedersen">Nancy L. Pedersen</name>
<affiliation wicri:level="3">
<nlm:aff id="aff2">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea>
<placeName>
<settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Prokopenko, Inga" sort="Prokopenko, Inga" uniqKey="Prokopenko I" first="Inga" last="Prokopenko">Inga Prokopenko</name>
<affiliation wicri:level="4">
<nlm:aff id="aff62">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea>
<placeName>
<settlement type="city">Oxford</settlement>
<region type="country">Angleterre</region>
<region type="comté" nuts="2">Oxfordshire</region>
<settlement type="city">Oxford</settlement>
</placeName>
<orgName type="university">Université d'Oxford</orgName>
</affiliation>
<affiliation wicri:level="3">
<nlm:aff id="aff63">Department of Genomics of Common Disease, School of Public Health, Imperial College London, London, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Genomics of Common Disease, School of Public Health, Imperial College London, London</wicri:regionArea>
<placeName>
<settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
<affiliation wicri:level="4">
<nlm:aff id="aff64">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford</wicri:regionArea>
<placeName>
<settlement type="city">Oxford</settlement>
<region type="country">Angleterre</region>
<region type="comté" nuts="2">Oxfordshire</region>
<settlement type="city">Oxford</settlement>
</placeName>
<orgName type="university">Université d'Oxford</orgName>
</affiliation>
</author>
<author>
<name sortKey="Mccarthy, Mark I" sort="Mccarthy, Mark I" uniqKey="Mccarthy M" first="Mark I." last="Mccarthy">Mark I. Mccarthy</name>
<affiliation wicri:level="4">
<nlm:aff id="aff62">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea>
<placeName>
<settlement type="city">Oxford</settlement>
<region type="country">Angleterre</region>
<region type="comté" nuts="2">Oxfordshire</region>
<settlement type="city">Oxford</settlement>
</placeName>
<orgName type="university">Université d'Oxford</orgName>
</affiliation>
<affiliation wicri:level="4">
<nlm:aff id="aff64">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford</wicri:regionArea>
<placeName>
<settlement type="city">Oxford</settlement>
<region type="country">Angleterre</region>
<region type="comté" nuts="2">Oxfordshire</region>
<settlement type="city">Oxford</settlement>
</placeName>
<orgName type="university">Université d'Oxford</orgName>
</affiliation>
<affiliation wicri:level="3">
<nlm:aff id="aff65">Oxford National Institute for Health Research Biomedical Research Centre, Churchill Hospital, Oxford, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Oxford National Institute for Health Research Biomedical Research Centre, Churchill Hospital, Oxford</wicri:regionArea>
<placeName>
<settlement type="city">Oxford</settlement>
<region type="country">Angleterre</region>
<region type="comté" nuts="2">Oxfordshire</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Ingelsson, Erik" sort="Ingelsson, Erik" uniqKey="Ingelsson E" first="Erik" last="Ingelsson">Erik Ingelsson</name>
<affiliation wicri:level="4">
<nlm:aff id="aff1">Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala</wicri:regionArea>
<orgName type="university">Université d'Uppsala</orgName>
<placeName>
<settlement type="city">Uppsala</settlement>
<region nuts="1">Svealand</region>
<region nuts="1">East Middle Sweden</region>
</placeName>
</affiliation>
<affiliation wicri:level="4">
<nlm:aff id="aff62">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea>
<placeName>
<settlement type="city">Oxford</settlement>
<region type="country">Angleterre</region>
<region type="comté" nuts="2">Oxfordshire</region>
<settlement type="city">Oxford</settlement>
</placeName>
<orgName type="university">Université d'Oxford</orgName>
</affiliation>
</author>
</analytic>
<series>
<title level="j">Diabetes</title>
<idno type="ISSN">0012-1797</idno>
<idno type="eISSN">1939-327X</idno>
<imprint>
<date when="2015">2015</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc>
<textClass>
<keywords scheme="KwdEn" xml:lang="en">
<term>Adiposity (physiology)</term>
<term>Aging (physiology)</term>
<term>Blood Pressure</term>
<term>C-Reactive Protein (metabolism)</term>
<term>Cardiovascular Diseases (metabolism)</term>
<term>Cholesterol, HDL (blood)</term>
<term>Cholesterol, HDL (metabolism)</term>
<term>Female</term>
<term>Humans</term>
<term>Insulin (blood)</term>
<term>Interleukin-6</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Sex Factors</term>
<term>Triglycerides (blood)</term>
<term>Triglycerides (metabolism)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr">
<term>Adiposité (physiologie)</term>
<term>Adulte d'âge moyen</term>
<term>Cholestérol HDL (métabolisme)</term>
<term>Cholestérol HDL (sang)</term>
<term>Facteurs sexuels</term>
<term>Femelle</term>
<term>Humains</term>
<term>Insuline (sang)</term>
<term>Interleukine-6</term>
<term>Maladies cardiovasculaires (métabolisme)</term>
<term>Mâle</term>
<term>Pression sanguine</term>
<term>Protéine C-réactive (métabolisme)</term>
<term>Triglycéride (métabolisme)</term>
<term>Triglycéride (sang)</term>
<term>Vieillissement (physiologie)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en">
<term>Cholesterol, HDL</term>
<term>Insulin</term>
<term>Triglycerides</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en">
<term>C-Reactive Protein</term>
<term>Cholesterol, HDL</term>
<term>Triglycerides</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en">
<term>Cardiovascular Diseases</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr">
<term>Cholestérol HDL</term>
<term>Maladies cardiovasculaires</term>
<term>Protéine C-réactive</term>
<term>Triglycéride</term>
</keywords>
<keywords scheme="MESH" qualifier="physiologie" xml:lang="fr">
<term>Adiposité</term>
<term>Vieillissement</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en">
<term>Adiposity</term>
<term>Aging</term>
</keywords>
<keywords scheme="MESH" qualifier="sang" xml:lang="fr">
<term>Cholestérol HDL</term>
<term>Insuline</term>
<term>Triglycéride</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Blood Pressure</term>
<term>Female</term>
<term>Humans</term>
<term>Interleukin-6</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Sex Factors</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr">
<term>Adulte d'âge moyen</term>
<term>Facteurs sexuels</term>
<term>Femelle</term>
<term>Humains</term>
<term>Interleukine-6</term>
<term>Mâle</term>
<term>Pression sanguine</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">
<p>Observational studies have reported different effects of adiposity on cardiovascular risk factors across age and sex. Since cardiovascular risk factors are enriched in obese individuals, it has not been easy to dissect the effects of adiposity from those of other risk factors. We used a Mendelian randomization approach, applying a set of 32 genetic markers to estimate the causal effect of adiposity on blood pressure, glycemic indices, circulating lipid levels, and markers of inflammation and liver disease in up to 67,553 individuals. All analyses were stratified by age (cutoff 55 years of age) and sex. The genetic score was associated with BMI in both nonstratified analysis (
<italic>P</italic>
= 2.8 × 10
<sup>−107</sup>
) and stratified analyses (all
<italic>P</italic>
< 3.3 × 10
<sup>−30</sup>
). We found evidence of a causal effect of adiposity on blood pressure, fasting levels of insulin, C-reactive protein, interleukin-6, HDL cholesterol, and triglycerides in a nonstratified analysis and in the <55-year stratum. Further, we found evidence of a smaller causal effect on total cholesterol (
<italic>P</italic>
for difference = 0.015) in the ≥55-year stratum than in the <55-year stratum, a finding that could be explained by biology, survival bias, or differential medication. In conclusion, this study extends previous knowledge of the effects of adiposity by providing sex- and age-specific causal estimates on cardiovascular risk factors.</p>
</div>
</front>
<back>
<div1 type="bibliography">
<listBibl>
<biblStruct>
<analytic>
<author>
<name sortKey="Gersh, Bj" uniqKey="Gersh B">BJ Gersh</name>
</author>
<author>
<name sortKey="Sliwa, K" uniqKey="Sliwa K">K Sliwa</name>
</author>
<author>
<name sortKey="Mayosi, Bm" uniqKey="Mayosi B">BM Mayosi</name>
</author>
<author>
<name sortKey="Yusuf, S" uniqKey="Yusuf S">S Yusuf</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Wenger, Nk" uniqKey="Wenger N">NK Wenger</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Anand, Ss" uniqKey="Anand S">SS Anand</name>
</author>
<author>
<name sortKey="Islam, S" uniqKey="Islam S">S Islam</name>
</author>
<author>
<name sortKey="Rosengren, A" uniqKey="Rosengren A">A Rosengren</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Dow, Ca" uniqKey="Dow C">CA Dow</name>
</author>
<author>
<name sortKey="Thomson, Ca" uniqKey="Thomson C">CA Thomson</name>
</author>
<author>
<name sortKey="Flatt, Sw" uniqKey="Flatt S">SW Flatt</name>
</author>
<author>
<name sortKey="Sherwood, Ne" uniqKey="Sherwood N">NE Sherwood</name>
</author>
<author>
<name sortKey="Pakiz, B" uniqKey="Pakiz B">B Pakiz</name>
</author>
<author>
<name sortKey="Rock, Cl" uniqKey="Rock C">CL Rock</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Siebenhofer, A" uniqKey="Siebenhofer A">A Siebenhofer</name>
</author>
<author>
<name sortKey="Jeitler, K" uniqKey="Jeitler K">K Jeitler</name>
</author>
<author>
<name sortKey="Berghold, A" uniqKey="Berghold A">A Berghold</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Madsbad, S" uniqKey="Madsbad S">S Madsbad</name>
</author>
<author>
<name sortKey="Dirksen, C" uniqKey="Dirksen C">C Dirksen</name>
</author>
<author>
<name sortKey="Holst, Jj" uniqKey="Holst J">JJ Holst</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Fall, T" uniqKey="Fall T">T Fall</name>
</author>
<author>
<name sortKey="H Gg, S" uniqKey="H Gg S">S Hägg</name>
</author>
<author>
<name sortKey="M Gi, R" uniqKey="M Gi R">R Mägi</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Nordestgaard, Bg" uniqKey="Nordestgaard B">BG Nordestgaard</name>
</author>
<author>
<name sortKey="Palmer, Tm" uniqKey="Palmer T">TM Palmer</name>
</author>
<author>
<name sortKey="Benn, M" uniqKey="Benn M">M Benn</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Sheehan, Na" uniqKey="Sheehan N">NA Sheehan</name>
</author>
<author>
<name sortKey="Didelez, V" uniqKey="Didelez V">V Didelez</name>
</author>
<author>
<name sortKey="Burton, Pr" uniqKey="Burton P">PR Burton</name>
</author>
<author>
<name sortKey="Tobin, Md" uniqKey="Tobin M">MD Tobin</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Mendelsohn, Me" uniqKey="Mendelsohn M">ME Mendelsohn</name>
</author>
<author>
<name sortKey="Karas, Rh" uniqKey="Karas R">RH Karas</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Tchernof, A" uniqKey="Tchernof A">A Tchernof</name>
</author>
<author>
<name sortKey="Despres, Jp" uniqKey="Despres J">JP Després</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Geer, Eb" uniqKey="Geer E">EB Geer</name>
</author>
<author>
<name sortKey="Shen, W" uniqKey="Shen W">W Shen</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Pikilidou, Mi" uniqKey="Pikilidou M">MI Pikilidou</name>
</author>
<author>
<name sortKey="Scuteri, A" uniqKey="Scuteri A">A Scuteri</name>
</author>
<author>
<name sortKey="Morrell, C" uniqKey="Morrell C">C Morrell</name>
</author>
<author>
<name sortKey="Lakatta, Eg" uniqKey="Lakatta E">EG Lakatta</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Whitlock, G" uniqKey="Whitlock G">G Whitlock</name>
</author>
<author>
<name sortKey="Lewington, S" uniqKey="Lewington S">S Lewington</name>
</author>
<author>
<name sortKey="Sherliker, P" uniqKey="Sherliker P">P Sherliker</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Chen, Y" uniqKey="Chen Y">Y Chen</name>
</author>
<author>
<name sortKey="Rennie, Dc" uniqKey="Rennie D">DC Rennie</name>
</author>
<author>
<name sortKey="Reeder, Ba" uniqKey="Reeder B">BA Reeder</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Wakabayashi, I" uniqKey="Wakabayashi I">I Wakabayashi</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Wakabayashi, I" uniqKey="Wakabayashi I">I Wakabayashi</name>
</author>
<author>
<name sortKey="Daimon, T" uniqKey="Daimon T">T Daimon</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Berrington De Gonzalez, A" uniqKey="Berrington De Gonzalez A">A Berrington de Gonzalez</name>
</author>
<author>
<name sortKey="Hartge, P" uniqKey="Hartge P">P Hartge</name>
</author>
<author>
<name sortKey="Cerhan, Jr" uniqKey="Cerhan J">JR Cerhan</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Speliotes, Ek" uniqKey="Speliotes E">EK Speliotes</name>
</author>
<author>
<name sortKey="Willer, Cj" uniqKey="Willer C">CJ Willer</name>
</author>
<author>
<name sortKey="Berndt, Si" uniqKey="Berndt S">SI Berndt</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="De Bakker, Pi" uniqKey="De Bakker P">PI de Bakker</name>
</author>
<author>
<name sortKey="Ferreira, Ma" uniqKey="Ferreira M">MA Ferreira</name>
</author>
<author>
<name sortKey="Jia, X" uniqKey="Jia X">X Jia</name>
</author>
<author>
<name sortKey="Neale, Bm" uniqKey="Neale B">BM Neale</name>
</author>
<author>
<name sortKey="Raychaudhuri, S" uniqKey="Raychaudhuri S">S Raychaudhuri</name>
</author>
<author>
<name sortKey="Voight, Bf" uniqKey="Voight B">BF Voight</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Palmer, Tm" uniqKey="Palmer T">TM Palmer</name>
</author>
<author>
<name sortKey="Sterne, Ja" uniqKey="Sterne J">JA Sterne</name>
</author>
<author>
<name sortKey="Harbord, Rm" uniqKey="Harbord R">RM Harbord</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Benjamini, Y" uniqKey="Benjamini Y">Y Benjamini</name>
</author>
<author>
<name sortKey="Hochberg, Y" uniqKey="Hochberg Y">Y Hochberg</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Makki, K" uniqKey="Makki K">K Makki</name>
</author>
<author>
<name sortKey="Froguel, P" uniqKey="Froguel P">P Froguel</name>
</author>
<author>
<name sortKey="Wolowczuk, I" uniqKey="Wolowczuk I">I Wolowczuk</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Ouchi, N" uniqKey="Ouchi N">N Ouchi</name>
</author>
<author>
<name sortKey="Parker, Jl" uniqKey="Parker J">JL Parker</name>
</author>
<author>
<name sortKey="Lugus, Jj" uniqKey="Lugus J">JJ Lugus</name>
</author>
<author>
<name sortKey="Walsh, K" uniqKey="Walsh K">K Walsh</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Gao, H" uniqKey="Gao H">H Gao</name>
</author>
<author>
<name sortKey="Fall, T" uniqKey="Fall T">T Fall</name>
</author>
<author>
<name sortKey="Van Dam, Rm" uniqKey="Van Dam R">RM van Dam</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Landsberg, L" uniqKey="Landsberg L">L Landsberg</name>
</author>
<author>
<name sortKey="Aronne, Lj" uniqKey="Aronne L">LJ Aronne</name>
</author>
<author>
<name sortKey="Beilin, Lj" uniqKey="Beilin L">LJ Beilin</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Reaven, Gm" uniqKey="Reaven G">GM Reaven</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Asrih, M" uniqKey="Asrih M">M Asrih</name>
</author>
<author>
<name sortKey="Jornayvaz, Fr" uniqKey="Jornayvaz F">FR Jornayvaz</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Racette, Sb" uniqKey="Racette S">SB Racette</name>
</author>
<author>
<name sortKey="Evans, Em" uniqKey="Evans E">EM Evans</name>
</author>
<author>
<name sortKey="Weiss, Ep" uniqKey="Weiss E">EP Weiss</name>
</author>
<author>
<name sortKey="Hagberg, Jm" uniqKey="Hagberg J">JM Hagberg</name>
</author>
<author>
<name sortKey="Holloszy, Jo" uniqKey="Holloszy J">JO Holloszy</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Sierra Johnson, J" uniqKey="Sierra Johnson J">J Sierra-Johnson</name>
</author>
<author>
<name sortKey="Johnson, Bd" uniqKey="Johnson B">BD Johnson</name>
</author>
<author>
<name sortKey="Bailey, Kr" uniqKey="Bailey K">KR Bailey</name>
</author>
<author>
<name sortKey="Turner, St" uniqKey="Turner S">ST Turner</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Thorand, B" uniqKey="Thorand B">B Thorand</name>
</author>
<author>
<name sortKey="Baumert, J" uniqKey="Baumert J">J Baumert</name>
</author>
<author>
<name sortKey="Doring, A" uniqKey="Doring A">A Döring</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Lear, Sa" uniqKey="Lear S">SA Lear</name>
</author>
<author>
<name sortKey="Chen, Mm" uniqKey="Chen M">MM Chen</name>
</author>
<author>
<name sortKey="Birmingham, Cl" uniqKey="Birmingham C">CL Birmingham</name>
</author>
<author>
<name sortKey="Frohlich, Jj" uniqKey="Frohlich J">JJ Frohlich</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Rossi, Ia" uniqKey="Rossi I">IA Rossi</name>
</author>
<author>
<name sortKey="Bochud, M" uniqKey="Bochud M">M Bochud</name>
</author>
<author>
<name sortKey="Bovet, P" uniqKey="Bovet P">P Bovet</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Visser, M" uniqKey="Visser M">M Visser</name>
</author>
<author>
<name sortKey="Bouter, Lm" uniqKey="Bouter L">LM Bouter</name>
</author>
<author>
<name sortKey="Mcquillan, Gm" uniqKey="Mcquillan G">GM McQuillan</name>
</author>
<author>
<name sortKey="Wener, Mh" uniqKey="Wener M">MH Wener</name>
</author>
<author>
<name sortKey="Harris, Tb" uniqKey="Harris T">TB Harris</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Pascot, A" uniqKey="Pascot A">A Pascot</name>
</author>
<author>
<name sortKey="Lemieux, S" uniqKey="Lemieux S">S Lemieux</name>
</author>
<author>
<name sortKey="Lemieux, I" uniqKey="Lemieux I">I Lemieux</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Darmon, P" uniqKey="Darmon P">P Darmon</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Davey Smith, G" uniqKey="Davey Smith G">G Davey Smith</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Burgess, S" uniqKey="Burgess S">S Burgess</name>
</author>
<author>
<name sortKey="Thompson, Sg" uniqKey="Thompson S">SG Thompson</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Willer, Cj" uniqKey="Willer C">CJ Willer</name>
</author>
<author>
<name sortKey="Schmidt, Em" uniqKey="Schmidt E">EM Schmidt</name>
</author>
<author>
<name sortKey="Sengupta, S" uniqKey="Sengupta S">S Sengupta</name>
</author>
</analytic>
</biblStruct>
</listBibl>
</div1>
</back>
</TEI>
<affiliations>
<list>
<country>
<li>Allemagne</li>
<li>Australie</li>
<li>Danemark</li>
<li>Espagne</li>
<li>Estonie</li>
<li>Finlande</li>
<li>France</li>
<li>Italie</li>
<li>Pays-Bas</li>
<li>Royaume-Uni</li>
<li>Suède</li>
<li>États-Unis</li>
</country>
<region>
<li>Alsace (région administrative)</li>
<li>Angleterre</li>
<li>Bade-Wurtemberg</li>
<li>Bavière</li>
<li>Communauté de Madrid</li>
<li>District de Düsseldorf</li>
<li>District de Haute-Bavière</li>
<li>District de Tübingen</li>
<li>East Middle Sweden</li>
<li>Finlande occidentale</li>
<li>Grand Est</li>
<li>Grand Londres</li>
<li>Hollande-Méridionale</li>
<li>Hollande-Septentrionale</li>
<li>Massachusetts</li>
<li>Midi-Pyrénées</li>
<li>Occitanie (région administrative)</li>
<li>Oxfordshire</li>
<li>Rhénanie-du-Nord-Westphalie</li>
<li>Svealand</li>
<li>Uusimaa</li>
<li>Yorkshire-et-Humber</li>
<li>Île-de-France</li>
</region>
<settlement>
<li>Amsterdam</li>
<li>Düsseldorf</li>
<li>Helsinki</li>
<li>Leeds</li>
<li>Londres</li>
<li>Madrid</li>
<li>Munich</li>
<li>Oxford</li>
<li>Paris</li>
<li>Rotterdam</li>
<li>Stockholm</li>
<li>Strasbourg</li>
<li>Toulouse</li>
<li>Turku</li>
<li>Ulm</li>
<li>Uppsala</li>
</settlement>
<orgName>
<li>Université d'Helsinki</li>
<li>Université d'Oxford</li>
<li>Université d'Uppsala</li>
<li>Université de Leeds</li>
<li>Université de Londres</li>
</orgName>
</list>
<tree>
<country name="Suède">
<region name="Svealand">
<name sortKey="Fall, Tove" sort="Fall, Tove" uniqKey="Fall T" first="Tove" last="Fall">Tove Fall</name>
</region>
<name sortKey=" Kerlund, Mikael" sort=" Kerlund, Mikael" uniqKey=" Kerlund M" first="Mikael" last=" Kerlund">Mikael Kerlund</name>
<name sortKey="Giedraitis, Vilmantas" sort="Giedraitis, Vilmantas" uniqKey="Giedraitis V" first="Vilmantas" last="Giedraitis">Vilmantas Giedraitis</name>
<name sortKey="Groop, Leif" sort="Groop, Leif" uniqKey="Groop L" first="Leif" last="Groop">Leif Groop</name>
<name sortKey="H Gg, Sara" sort="H Gg, Sara" uniqKey="H Gg S" first="Sara" last="H Gg">Sara H Gg</name>
<name sortKey="H Gg, Sara" sort="H Gg, Sara" uniqKey="H Gg S" first="Sara" last="H Gg">Sara H Gg</name>
<name sortKey="Ingelsson, Erik" sort="Ingelsson, Erik" uniqKey="Ingelsson E" first="Erik" last="Ingelsson">Erik Ingelsson</name>
<name sortKey="Ladenvall, Claes" sort="Ladenvall, Claes" uniqKey="Ladenvall C" first="Claes" last="Ladenvall">Claes Ladenvall</name>
<name sortKey="Lind, Lars" sort="Lind, Lars" uniqKey="Lind L" first="Lars" last="Lind">Lars Lind</name>
<name sortKey="Lyssenko, Valeriya" sort="Lyssenko, Valeriya" uniqKey="Lyssenko V" first="Valeriya" last="Lyssenko">Valeriya Lyssenko</name>
<name sortKey="Magnusson, Patrik K" sort="Magnusson, Patrik K" uniqKey="Magnusson P" first="Patrik K." last="Magnusson">Patrik K. Magnusson</name>
<name sortKey="Nilsson, Peter M" sort="Nilsson, Peter M" uniqKey="Nilsson P" first="Peter M." last="Nilsson">Peter M. Nilsson</name>
<name sortKey="Pedersen, Nancy L" sort="Pedersen, Nancy L" uniqKey="Pedersen N" first="Nancy L." last="Pedersen">Nancy L. Pedersen</name>
<name sortKey="Ploner, Alexander" sort="Ploner, Alexander" uniqKey="Ploner A" first="Alexander" last="Ploner">Alexander Ploner</name>
<name sortKey="Syv Nen, Ann Christine" sort="Syv Nen, Ann Christine" uniqKey="Syv Nen A" first="Ann-Christine" last="Syv Nen">Ann-Christine Syv Nen</name>
</country>
<country name="Estonie">
<noRegion>
<name sortKey="M Gi, Reedik" sort="M Gi, Reedik" uniqKey="M Gi R" first="Reedik" last="M Gi">Reedik M Gi</name>
</noRegion>
<name sortKey="Esko, T Nu" sort="Esko, T Nu" uniqKey="Esko T" first="T Nu" last="Esko">T Nu Esko</name>
<name sortKey="Fischer, Krista" sort="Fischer, Krista" uniqKey="Fischer K" first="Krista" last="Fischer">Krista Fischer</name>
<name sortKey="Kals, Mart" sort="Kals, Mart" uniqKey="Kals M" first="Mart" last="Kals">Mart Kals</name>
<name sortKey="Kals, Mart" sort="Kals, Mart" uniqKey="Kals M" first="Mart" last="Kals">Mart Kals</name>
<name sortKey="Metspalu, Andres" sort="Metspalu, Andres" uniqKey="Metspalu A" first="Andres" last="Metspalu">Andres Metspalu</name>
</country>
<country name="Pays-Bas">
<region name="Hollande-Septentrionale">
<name sortKey="Draisma, Harmen H M" sort="Draisma, Harmen H M" uniqKey="Draisma H" first="Harmen H. M." last="Draisma">Harmen H. M. Draisma</name>
</region>
<name sortKey="Boomsma, Dorret I" sort="Boomsma, Dorret I" uniqKey="Boomsma D" first="Dorret I." last="Boomsma">Dorret I. Boomsma</name>
<name sortKey="Boomsma, Dorret I" sort="Boomsma, Dorret I" uniqKey="Boomsma D" first="Dorret I." last="Boomsma">Dorret I. Boomsma</name>
<name sortKey="De Bruijn, Renee F A G" sort="De Bruijn, Renee F A G" uniqKey="De Bruijn R" first="Renée F. A. G." last="De Bruijn">Renée F. A. G. De Bruijn</name>
<name sortKey="De Bruijn, Renee F A G" sort="De Bruijn, Renee F A G" uniqKey="De Bruijn R" first="Renée F. A. G." last="De Bruijn">Renée F. A. G. De Bruijn</name>
<name sortKey="De Vries, Paul S" sort="De Vries, Paul S" uniqKey="De Vries P" first="Paul S." last="De Vries">Paul S. De Vries</name>
<name sortKey="Dehghan, Abbas" sort="Dehghan, Abbas" uniqKey="Dehghan A" first="Abbas" last="Dehghan">Abbas Dehghan</name>
<name sortKey="Draisma, Harmen H M" sort="Draisma, Harmen H M" uniqKey="Draisma H" first="Harmen H. M." last="Draisma">Harmen H. M. Draisma</name>
<name sortKey="Franco, Oscar H" sort="Franco, Oscar H" uniqKey="Franco O" first="Oscar H." last="Franco">Oscar H. Franco</name>
<name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name>
<name sortKey="Ikram, M Arfan" sort="Ikram, M Arfan" uniqKey="Ikram M" first="M. Arfan" last="Ikram">M. Arfan Ikram</name>
<name sortKey="Ikram, M Arfan" sort="Ikram, M Arfan" uniqKey="Ikram M" first="M. Arfan" last="Ikram">M. Arfan Ikram</name>
<name sortKey="Kuningas, Maris" sort="Kuningas, Maris" uniqKey="Kuningas M" first="Maris" last="Kuningas">Maris Kuningas</name>
<name sortKey="Kuningas, Maris" sort="Kuningas, Maris" uniqKey="Kuningas M" first="Maris" last="Kuningas">Maris Kuningas</name>
<name sortKey="Penninx, Brenda W" sort="Penninx, Brenda W" uniqKey="Penninx B" first="Brenda W." last="Penninx">Brenda W. Penninx</name>
<name sortKey="Penninx, Brenda W" sort="Penninx, Brenda W" uniqKey="Penninx B" first="Brenda W." last="Penninx">Brenda W. Penninx</name>
<name sortKey="Stricker, Bruno H" sort="Stricker, Bruno H" uniqKey="Stricker B" first="Bruno H." last="Stricker">Bruno H. Stricker</name>
<name sortKey="Stricker, Bruno H" sort="Stricker, Bruno H" uniqKey="Stricker B" first="Bruno H." last="Stricker">Bruno H. Stricker</name>
<name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="André G." last="Uitterlinden">André G. Uitterlinden</name>
<name sortKey="Van Duijn, Cornelia M" sort="Van Duijn, Cornelia M" uniqKey="Van Duijn C" first="Cornelia M." last="Van Duijn">Cornelia M. Van Duijn</name>
<name sortKey="Willems, Sara M" sort="Willems, Sara M" uniqKey="Willems S" first="Sara M." last="Willems">Sara M. Willems</name>
</country>
<country name="Finlande">
<region name="Uusimaa">
<name sortKey="Sarin, Antti Pekka" sort="Sarin, Antti Pekka" uniqKey="Sarin A" first="Antti-Pekka" last="Sarin">Antti-Pekka Sarin</name>
</region>
<name sortKey="Groop, Leif" sort="Groop, Leif" uniqKey="Groop L" first="Leif" last="Groop">Leif Groop</name>
<name sortKey="Havulinna, Aki S" sort="Havulinna, Aki S" uniqKey="Havulinna A" first="Aki S." last="Havulinna">Aki S. Havulinna</name>
<name sortKey="Heikkil, Kauko" sort="Heikkil, Kauko" uniqKey="Heikkil K" first="Kauko" last="Heikkil">Kauko Heikkil</name>
<name sortKey="Huikari, Ville" sort="Huikari, Ville" uniqKey="Huikari V" first="Ville" last="Huikari">Ville Huikari</name>
<name sortKey="J Rvelin, Marjo Riitta" sort="J Rvelin, Marjo Riitta" uniqKey="J Rvelin M" first="Marjo-Riitta" last="J Rvelin">Marjo-Riitta J Rvelin</name>
<name sortKey="J Rvelin, Marjo Riitta" sort="J Rvelin, Marjo Riitta" uniqKey="J Rvelin M" first="Marjo-Riitta" last="J Rvelin">Marjo-Riitta J Rvelin</name>
<name sortKey="J Rvelin, Marjo Riitta" sort="J Rvelin, Marjo Riitta" uniqKey="J Rvelin M" first="Marjo-Riitta" last="J Rvelin">Marjo-Riitta J Rvelin</name>
<name sortKey="Jula, Antti" sort="Jula, Antti" uniqKey="Jula A" first="Antti" last="Jula">Antti Jula</name>
<name sortKey="Kaakinen, Marika" sort="Kaakinen, Marika" uniqKey="Kaakinen M" first="Marika" last="Kaakinen">Marika Kaakinen</name>
<name sortKey="Kaprio, Jaakko" sort="Kaprio, Jaakko" uniqKey="Kaprio J" first="Jaakko" last="Kaprio">Jaakko Kaprio</name>
<name sortKey="Kaprio, Jaakko" sort="Kaprio, Jaakko" uniqKey="Kaprio J" first="Jaakko" last="Kaprio">Jaakko Kaprio</name>
<name sortKey="Kaprio, Jaakko" sort="Kaprio, Jaakko" uniqKey="Kaprio J" first="Jaakko" last="Kaprio">Jaakko Kaprio</name>
<name sortKey="Kristiansson, Kati" sort="Kristiansson, Kati" uniqKey="Kristiansson K" first="Kati" last="Kristiansson">Kati Kristiansson</name>
<name sortKey="Kuulasmaa, Kari" sort="Kuulasmaa, Kari" uniqKey="Kuulasmaa K" first="Kari" last="Kuulasmaa">Kari Kuulasmaa</name>
<name sortKey="Nuotio, Marja Liisa" sort="Nuotio, Marja Liisa" uniqKey="Nuotio M" first="Marja-Liisa" last="Nuotio">Marja-Liisa Nuotio</name>
<name sortKey="Palotie, Aarno" sort="Palotie, Aarno" uniqKey="Palotie A" first="Aarno" last="Palotie">Aarno Palotie</name>
<name sortKey="Palotie, Aarno" sort="Palotie, Aarno" uniqKey="Palotie A" first="Aarno" last="Palotie">Aarno Palotie</name>
<name sortKey="Perola, Markus" sort="Perola, Markus" uniqKey="Perola M" first="Markus" last="Perola">Markus Perola</name>
<name sortKey="Pietil Inen, Kirsi H" sort="Pietil Inen, Kirsi H" uniqKey="Pietil Inen K" first="Kirsi H." last="Pietil Inen">Kirsi H. Pietil Inen</name>
<name sortKey="Pietil Inen, Kirsi H" sort="Pietil Inen, Kirsi H" uniqKey="Pietil Inen K" first="Kirsi H." last="Pietil Inen">Kirsi H. Pietil Inen</name>
<name sortKey="Pietil Inen, Kirsi H" sort="Pietil Inen, Kirsi H" uniqKey="Pietil Inen K" first="Kirsi H." last="Pietil Inen">Kirsi H. Pietil Inen</name>
<name sortKey="Ripatti, Samuli" sort="Ripatti, Samuli" uniqKey="Ripatti S" first="Samuli" last="Ripatti">Samuli Ripatti</name>
<name sortKey="Ripatti, Samuli" sort="Ripatti, Samuli" uniqKey="Ripatti S" first="Samuli" last="Ripatti">Samuli Ripatti</name>
<name sortKey="Ripatti, Samuli" sort="Ripatti, Samuli" uniqKey="Ripatti S" first="Samuli" last="Ripatti">Samuli Ripatti</name>
<name sortKey="Salomaa, Veikko" sort="Salomaa, Veikko" uniqKey="Salomaa V" first="Veikko" last="Salomaa">Veikko Salomaa</name>
<name sortKey="Sarin, Antti Pekka" sort="Sarin, Antti Pekka" uniqKey="Sarin A" first="Antti-Pekka" last="Sarin">Antti-Pekka Sarin</name>
<name sortKey="Silventoinen, Karri" sort="Silventoinen, Karri" uniqKey="Silventoinen K" first="Karri" last="Silventoinen">Karri Silventoinen</name>
<name sortKey="Virtamo, Jarmo" sort="Virtamo, Jarmo" uniqKey="Virtamo J" first="Jarmo" last="Virtamo">Jarmo Virtamo</name>
</country>
<country name="Australie">
<noRegion>
<name sortKey="Benyamin, Beben" sort="Benyamin, Beben" uniqKey="Benyamin B" first="Beben" last="Benyamin">Beben Benyamin</name>
</noRegion>
<name sortKey="Benyamin, Beben" sort="Benyamin, Beben" uniqKey="Benyamin B" first="Beben" last="Benyamin">Beben Benyamin</name>
<name sortKey="Martin, Nicholas G" sort="Martin, Nicholas G" uniqKey="Martin N" first="Nicholas G." last="Martin">Nicholas G. Martin</name>
<name sortKey="Montgomery, Grant W" sort="Montgomery, Grant W" uniqKey="Montgomery G" first="Grant W." last="Montgomery">Grant W. Montgomery</name>
<name sortKey="Whitfield, John B" sort="Whitfield, John B" uniqKey="Whitfield J" first="John B." last="Whitfield">John B. Whitfield</name>
</country>
<country name="États-Unis">
<region name="Massachusetts">
<name sortKey="Esko, T Nu" sort="Esko, T Nu" uniqKey="Esko T" first="T Nu" last="Esko">T Nu Esko</name>
</region>
<name sortKey="Esko, T Nu" sort="Esko, T Nu" uniqKey="Esko T" first="T Nu" last="Esko">T Nu Esko</name>
<name sortKey="Esko, T Nu" sort="Esko, T Nu" uniqKey="Esko T" first="T Nu" last="Esko">T Nu Esko</name>
<name sortKey="Palotie, Aarno" sort="Palotie, Aarno" uniqKey="Palotie A" first="Aarno" last="Palotie">Aarno Palotie</name>
</country>
<country name="Royaume-Uni">
<noRegion>
<name sortKey="Nelson, Christopher P" sort="Nelson, Christopher P" uniqKey="Nelson C" first="Christopher P." last="Nelson">Christopher P. Nelson</name>
</noRegion>
<name sortKey="Evans, Alun" sort="Evans, Alun" uniqKey="Evans A" first="Alun" last="Evans">Alun Evans</name>
<name sortKey="Hall, Alistair S" sort="Hall, Alistair S" uniqKey="Hall A" first="Alistair S." last="Hall">Alistair S. Hall</name>
<name sortKey="Ingelsson, Erik" sort="Ingelsson, Erik" uniqKey="Ingelsson E" first="Erik" last="Ingelsson">Erik Ingelsson</name>
<name sortKey="J Rvelin, Marjo Riitta" sort="J Rvelin, Marjo Riitta" uniqKey="J Rvelin M" first="Marjo-Riitta" last="J Rvelin">Marjo-Riitta J Rvelin</name>
<name sortKey="Mangino, Massimo" sort="Mangino, Massimo" uniqKey="Mangino M" first="Massimo" last="Mangino">Massimo Mangino</name>
<name sortKey="Mccarthy, Mark I" sort="Mccarthy, Mark I" uniqKey="Mccarthy M" first="Mark I." last="Mccarthy">Mark I. Mccarthy</name>
<name sortKey="Mccarthy, Mark I" sort="Mccarthy, Mark I" uniqKey="Mccarthy M" first="Mark I." last="Mccarthy">Mark I. Mccarthy</name>
<name sortKey="Mccarthy, Mark I" sort="Mccarthy, Mark I" uniqKey="Mccarthy M" first="Mark I." last="Mccarthy">Mark I. Mccarthy</name>
<name sortKey="Menni, Cristina" sort="Menni, Cristina" uniqKey="Menni C" first="Cristina" last="Menni">Cristina Menni</name>
<name sortKey="Nelson, Christopher P" sort="Nelson, Christopher P" uniqKey="Nelson C" first="Christopher P." last="Nelson">Christopher P. Nelson</name>
<name sortKey="Prokopenko, Inga" sort="Prokopenko, Inga" uniqKey="Prokopenko I" first="Inga" last="Prokopenko">Inga Prokopenko</name>
<name sortKey="Prokopenko, Inga" sort="Prokopenko, Inga" uniqKey="Prokopenko I" first="Inga" last="Prokopenko">Inga Prokopenko</name>
<name sortKey="Prokopenko, Inga" sort="Prokopenko, Inga" uniqKey="Prokopenko I" first="Inga" last="Prokopenko">Inga Prokopenko</name>
<name sortKey="Ripatti, Samuli" sort="Ripatti, Samuli" uniqKey="Ripatti S" first="Samuli" last="Ripatti">Samuli Ripatti</name>
<name sortKey="Samani, Nilesh J" sort="Samani, Nilesh J" uniqKey="Samani N" first="Nilesh J." last="Samani">Nilesh J. Samani</name>
<name sortKey="Samani, Nilesh J" sort="Samani, Nilesh J" uniqKey="Samani N" first="Nilesh J." last="Samani">Nilesh J. Samani</name>
<name sortKey="Spector, Tim D" sort="Spector, Tim D" uniqKey="Spector T" first="Tim D." last="Spector">Tim D. Spector</name>
<name sortKey="Strachan, David P" sort="Strachan, David P" uniqKey="Strachan D" first="David P." last="Strachan">David P. Strachan</name>
<name sortKey="Tobin, Martin D" sort="Tobin, Martin D" uniqKey="Tobin M" first="Martin D." last="Tobin">Martin D. Tobin</name>
<name sortKey="Yarnell, John W G" sort="Yarnell, John W G" uniqKey="Yarnell J" first="John W. G." last="Yarnell">John W. G. Yarnell</name>
</country>
<country name="France">
<noRegion>
<name sortKey="Meirhaeghe, Aline" sort="Meirhaeghe, Aline" uniqKey="Meirhaeghe A" first="Aline" last="Meirhaeghe">Aline Meirhaeghe</name>
</noRegion>
<name sortKey="Amouyel, Philippe" sort="Amouyel, Philippe" uniqKey="Amouyel P" first="Philippe" last="Amouyel">Philippe Amouyel</name>
<name sortKey="Arveiler, Dominique" sort="Arveiler, Dominique" uniqKey="Arveiler D" first="Dominique" last="Arveiler">Dominique Arveiler</name>
<name sortKey="Cottel, Dominique" sort="Cottel, Dominique" uniqKey="Cottel D" first="Dominique" last="Cottel">Dominique Cottel</name>
<name sortKey="Dallongeville, Jean" sort="Dallongeville, Jean" uniqKey="Dallongeville J" first="Jean" last="Dallongeville">Jean Dallongeville</name>
<name sortKey="Ferrieres, Jean" sort="Ferrieres, Jean" uniqKey="Ferrieres J" first="Jean" last="Ferrières">Jean Ferrières</name>
<name sortKey="Goumidi, Louisa" sort="Goumidi, Louisa" uniqKey="Goumidi L" first="Louisa" last="Goumidi">Louisa Goumidi</name>
<name sortKey="Legry, Vanessa" sort="Legry, Vanessa" uniqKey="Legry V" first="Vanessa" last="Legry">Vanessa Legry</name>
<name sortKey="Tregouet, David Alexandre" sort="Tregouet, David Alexandre" uniqKey="Tregouet D" first="David-Alexandre" last="Tregouet">David-Alexandre Tregouet</name>
<name sortKey="Tregouet, David Alexandre" sort="Tregouet, David Alexandre" uniqKey="Tregouet D" first="David-Alexandre" last="Tregouet">David-Alexandre Tregouet</name>
<name sortKey="Tregouet, David Alexandre" sort="Tregouet, David Alexandre" uniqKey="Tregouet D" first="David-Alexandre" last="Tregouet">David-Alexandre Tregouet</name>
</country>
<country name="Allemagne">
<noRegion>
<name sortKey="Kobl, Michael" sort="Kobl, Michael" uniqKey="Kobl M" first="Michael" last="Kobl">Michael Kobl</name>
</noRegion>
<name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name>
<name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name>
<name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name>
<name sortKey="Grallert, Harald" sort="Grallert, Harald" uniqKey="Grallert H" first="Harald" last="Grallert">Harald Grallert</name>
<name sortKey="Grallert, Harald" sort="Grallert, Harald" uniqKey="Grallert H" first="Harald" last="Grallert">Harald Grallert</name>
<name sortKey="Grallert, Harald" sort="Grallert, Harald" uniqKey="Grallert H" first="Harald" last="Grallert">Harald Grallert</name>
<name sortKey="Herder, Christian" sort="Herder, Christian" uniqKey="Herder C" first="Christian" last="Herder">Christian Herder</name>
<name sortKey="Herder, Christian" sort="Herder, Christian" uniqKey="Herder C" first="Christian" last="Herder">Christian Herder</name>
<name sortKey="Koenig, Wolfgang" sort="Koenig, Wolfgang" uniqKey="Koenig W" first="Wolfgang" last="Koenig">Wolfgang Koenig</name>
<name sortKey="Lichtner, Peter" sort="Lichtner, Peter" uniqKey="Lichtner P" first="Peter" last="Lichtner">Peter Lichtner</name>
<name sortKey="Peters, Annette" sort="Peters, Annette" uniqKey="Peters A" first="Annette" last="Peters">Annette Peters</name>
<name sortKey="Strauch, Konstantin" sort="Strauch, Konstantin" uniqKey="Strauch K" first="Konstantin" last="Strauch">Konstantin Strauch</name>
<name sortKey="Strauch, Konstantin" sort="Strauch, Konstantin" uniqKey="Strauch K" first="Konstantin" last="Strauch">Konstantin Strauch</name>
</country>
<country name="Espagne">
<noRegion>
<name sortKey="Moreno, Luis A" sort="Moreno, Luis A" uniqKey="Moreno L" first="Luis A." last="Moreno">Luis A. Moreno</name>
</noRegion>
<name sortKey="Gonzalez Gross, Marcela" sort="Gonzalez Gross, Marcela" uniqKey="Gonzalez Gross M" first="Marcela" last="Gonzalez-Gross">Marcela Gonzalez-Gross</name>
</country>
<country name="Italie">
<noRegion>
<name sortKey="Veronesi, Giovanni" sort="Veronesi, Giovanni" uniqKey="Veronesi G" first="Giovanni" last="Veronesi">Giovanni Veronesi</name>
</noRegion>
<name sortKey="Brambilla, Paolo" sort="Brambilla, Paolo" uniqKey="Brambilla P" first="Paolo" last="Brambilla">Paolo Brambilla</name>
</country>
<country name="Danemark">
<noRegion>
<name sortKey="Lyssenko, Valeriya" sort="Lyssenko, Valeriya" uniqKey="Lyssenko V" first="Valeriya" last="Lyssenko">Valeriya Lyssenko</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003202 | SxmlIndent | more

Ou

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 003202 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Asie
   |area=    AustralieFrV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     PMC:4407863
   |texte=   Age- and Sex-Specific Causal Effects of Adiposity on Cardiovascular Risk Factors
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:25712996" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a AustralieFrV1
Wicri

This area was generated with Dilib version V0.6.33.
Data generation: Tue Dec 5 10:43:12 2017. Site generation: Tue Mar 5 14:07:20 2024